Complex, Crusty Calculi: A Case Study Report of Renal Transplant Lithiasis and Encrustation

Ureteric encrustation and lithiasis after renal transplantation are rare but not without risk of obstruction and graft loss. Patients are usually asymptomatic, and a majority present with graft dysfunction with imaging demonstrating hydronephrosis and rarely with acute graft pyelonephritis. We compa...

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Main Authors: Shriram Swaminathan, BMed, In-Ah Park, MBBS, Bobby Chacko, FRACP
Format: Article
Language:English
Published: Wolters Kluwer 2023-06-01
Series:Transplantation Direct
Online Access:http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001468
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author Shriram Swaminathan, BMed
In-Ah Park, MBBS
Bobby Chacko, FRACP
author_facet Shriram Swaminathan, BMed
In-Ah Park, MBBS
Bobby Chacko, FRACP
author_sort Shriram Swaminathan, BMed
collection DOAJ
description Ureteric encrustation and lithiasis after renal transplantation are rare but not without risk of obstruction and graft loss. Patients are usually asymptomatic, and a majority present with graft dysfunction with imaging demonstrating hydronephrosis and rarely with acute graft pyelonephritis. We compare a case of transplant lithiasis with encrusted pyelitis and highlight key differences in their presentation and workup. A key focus for transplant physicians is to recognize when dealing with transplant hydronephrosis that the presence of a high urine pH and pyuria should be a key indicator to suspect ureteric encrustation to look for a urease-producing organism, recognizing that such organisms require prolonged incubation with urine culturing for up to 72 h.
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spelling doaj.art-f6de7a7bbaea474faef192839e11f20a2023-06-30T01:53:18ZengWolters KluwerTransplantation Direct2373-87312023-06-0196e146810.1097/TXD.0000000000001468202306000-00002Complex, Crusty Calculi: A Case Study Report of Renal Transplant Lithiasis and EncrustationShriram Swaminathan, BMed0In-Ah Park, MBBS1Bobby Chacko, FRACP21 Nephrology and Transplantation Unit, John Hunter Hospital, Newcastle, NSW, Australia.1 Nephrology and Transplantation Unit, John Hunter Hospital, Newcastle, NSW, Australia.1 Nephrology and Transplantation Unit, John Hunter Hospital, Newcastle, NSW, Australia.Ureteric encrustation and lithiasis after renal transplantation are rare but not without risk of obstruction and graft loss. Patients are usually asymptomatic, and a majority present with graft dysfunction with imaging demonstrating hydronephrosis and rarely with acute graft pyelonephritis. We compare a case of transplant lithiasis with encrusted pyelitis and highlight key differences in their presentation and workup. A key focus for transplant physicians is to recognize when dealing with transplant hydronephrosis that the presence of a high urine pH and pyuria should be a key indicator to suspect ureteric encrustation to look for a urease-producing organism, recognizing that such organisms require prolonged incubation with urine culturing for up to 72 h.http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001468
spellingShingle Shriram Swaminathan, BMed
In-Ah Park, MBBS
Bobby Chacko, FRACP
Complex, Crusty Calculi: A Case Study Report of Renal Transplant Lithiasis and Encrustation
Transplantation Direct
title Complex, Crusty Calculi: A Case Study Report of Renal Transplant Lithiasis and Encrustation
title_full Complex, Crusty Calculi: A Case Study Report of Renal Transplant Lithiasis and Encrustation
title_fullStr Complex, Crusty Calculi: A Case Study Report of Renal Transplant Lithiasis and Encrustation
title_full_unstemmed Complex, Crusty Calculi: A Case Study Report of Renal Transplant Lithiasis and Encrustation
title_short Complex, Crusty Calculi: A Case Study Report of Renal Transplant Lithiasis and Encrustation
title_sort complex crusty calculi a case study report of renal transplant lithiasis and encrustation
url http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001468
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