Clinical Diagnosis and Treatment Recommendations for Ocular Toxicities of Target Therapy and Immune Checkpoint Inhibitor Therapy
The increasing use of target therapy and immunocheckpoint inhibitors in cancers has brought new hope of survival to patients with advanced tumors. However, more and more adverse side-effects and toxicities of these medications had been reported, affect almost all human organs including the eye. Thes...
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Format: | Article |
Language: | zho |
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Chinese Anti-Cancer Association; Chinese Antituberculosis Association
2019-10-01
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Series: | Chinese Journal of Lung Cancer |
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Online Access: | http://dx.doi.org/10.3779/j.issn.1009-3419.2019.10.09 |
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author | Xiaowei LIU Zheng WANG Chan ZHAO Hanping WANG Xiaoxiao GUO Jiaxin ZHOU Lian DUAN Xiaoyan SI Li ZHANG Yue LI Mengzhao WANG Juhong SHI Meifen ZHANG Li ZHANG |
author_facet | Xiaowei LIU Zheng WANG Chan ZHAO Hanping WANG Xiaoxiao GUO Jiaxin ZHOU Lian DUAN Xiaoyan SI Li ZHANG Yue LI Mengzhao WANG Juhong SHI Meifen ZHANG Li ZHANG |
author_sort | Xiaowei LIU |
collection | DOAJ |
description | The increasing use of target therapy and immunocheckpoint inhibitors in cancers has brought new hope of survival to patients with advanced tumors. However, more and more adverse side-effects and toxicities of these medications had been reported, affect almost all human organs including the eye. These adverse effects may affect the entire ocular tissues, like eyelid, eye lashes, conjunctiva, cornea, uvea, retina, optic nerve and so on, which are always been ignored by patients and doctors. In this paper we will summarize the characteristics of the related ocular diseases and give our advice on how to diagnose and manage these diseases. |
first_indexed | 2024-12-22T14:54:16Z |
format | Article |
id | doaj.art-f6df4ba394bd464db5f749e6d7fd8c87 |
institution | Directory Open Access Journal |
issn | 1009-3419 1999-6187 |
language | zho |
last_indexed | 2024-12-22T14:54:16Z |
publishDate | 2019-10-01 |
publisher | Chinese Anti-Cancer Association; Chinese Antituberculosis Association |
record_format | Article |
series | Chinese Journal of Lung Cancer |
spelling | doaj.art-f6df4ba394bd464db5f749e6d7fd8c872022-12-21T18:22:15ZzhoChinese Anti-Cancer Association; Chinese Antituberculosis AssociationChinese Journal of Lung Cancer1009-34191999-61872019-10-01221065366010.3779/j.issn.1009-3419.2019.10.09Clinical Diagnosis and Treatment Recommendations for Ocular Toxicities of Target Therapy and Immune Checkpoint Inhibitor TherapyXiaowei LIU0Zheng WANG1Chan ZHAO2Hanping WANG3Xiaoxiao GUO4Jiaxin ZHOU5Lian DUAN6Xiaoyan SI7Li ZHANG8Yue LI9Mengzhao WANG10Juhong SHI11Meifen ZHANG12Li ZHANG13Department of Ophthalmology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, ChinaDepartment of Ophthalmology, Beijing Hospital, Beijing 100730, ChinaDepartment of Ophthalmology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, ChinaDepartment of Respiratory Medicine, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, ChinaDepartment of Cardiology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, ChinaDepartment of Rheumatology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, ChinaDepartment of Endocrinology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, ChinaDepartment of Respiratory Medicine, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, ChinaDepartment of Clinical Laboratory, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, ChinaDepartment of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, ChinaDepartment of Respiratory Medicine, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, ChinaDepartment of Respiratory Medicine, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, ChinaDepartment of Ophthalmology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, ChinaDepartment of Respiratory Medicine, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, ChinaThe increasing use of target therapy and immunocheckpoint inhibitors in cancers has brought new hope of survival to patients with advanced tumors. However, more and more adverse side-effects and toxicities of these medications had been reported, affect almost all human organs including the eye. These adverse effects may affect the entire ocular tissues, like eyelid, eye lashes, conjunctiva, cornea, uvea, retina, optic nerve and so on, which are always been ignored by patients and doctors. In this paper we will summarize the characteristics of the related ocular diseases and give our advice on how to diagnose and manage these diseases.http://dx.doi.org/10.3779/j.issn.1009-3419.2019.10.09Target therapyImmune checkpoint inhibitorImmunotherapy-related toxicitiesOcular diseses |
spellingShingle | Xiaowei LIU Zheng WANG Chan ZHAO Hanping WANG Xiaoxiao GUO Jiaxin ZHOU Lian DUAN Xiaoyan SI Li ZHANG Yue LI Mengzhao WANG Juhong SHI Meifen ZHANG Li ZHANG Clinical Diagnosis and Treatment Recommendations for Ocular Toxicities of Target Therapy and Immune Checkpoint Inhibitor Therapy Chinese Journal of Lung Cancer Target therapy Immune checkpoint inhibitor Immunotherapy-related toxicities Ocular diseses |
title | Clinical Diagnosis and Treatment Recommendations for Ocular Toxicities of Target Therapy and Immune Checkpoint Inhibitor Therapy |
title_full | Clinical Diagnosis and Treatment Recommendations for Ocular Toxicities of Target Therapy and Immune Checkpoint Inhibitor Therapy |
title_fullStr | Clinical Diagnosis and Treatment Recommendations for Ocular Toxicities of Target Therapy and Immune Checkpoint Inhibitor Therapy |
title_full_unstemmed | Clinical Diagnosis and Treatment Recommendations for Ocular Toxicities of Target Therapy and Immune Checkpoint Inhibitor Therapy |
title_short | Clinical Diagnosis and Treatment Recommendations for Ocular Toxicities of Target Therapy and Immune Checkpoint Inhibitor Therapy |
title_sort | clinical diagnosis and treatment recommendations for ocular toxicities of target therapy and immune checkpoint inhibitor therapy |
topic | Target therapy Immune checkpoint inhibitor Immunotherapy-related toxicities Ocular diseses |
url | http://dx.doi.org/10.3779/j.issn.1009-3419.2019.10.09 |
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