Does Skin Bathing With Chlorhexidine Gluconate (2%) Affect the Carbapenem-resistant Enterobacteriaceae and Vancomycin-resistant Enterococcus Colonization in Pediatric Intensive Care?
Introduction: Carbapenem-resistant Enterobacteriaceae (CRE) and vancomycin-resistant Enterococcus (VRE) colonization and infections are important in the pediatric intensive care unit (PICU). This study aimed to investigate the effect of a 2% chlorhexidine gluconate (CHG) bath on VRE and CRE coloniza...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Bilimsel Tip Yayinevi
2021-03-01
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| Series: | Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi |
| Subjects: | |
| Online Access: | http://www.floradergisi.org/managete/fu_folder/2021-01/189-195%20Sevgi%20Topal.pdf |
| Summary: | Introduction: Carbapenem-resistant Enterobacteriaceae (CRE) and vancomycin-resistant Enterococcus (VRE) colonization and infections are important in the pediatric intensive care unit (PICU). This study aimed to investigate the effect of a 2% chlorhexidine gluconate (CHG) bath on VRE and CRE colonization.
Materials and Methods: Skin bathing was performed every other day with 2% CHG as of April 2019. The frequency of CRE and VRE colonization pre and post-intervention was evaluated. Rectal swab samples were taken within 7 days before and after skin bathing with CHG. Besides, VRE and CRE spontaneously negation rates within 14 day periods were examined.
Results: The number of CRE positive patients within the CHG group were detected as 10 (47.6%) before using CHG and as 8 (38%) after using (OR: 1.5, p= 0.131, 95% CI: 0.87-1.98). The number of VRE positive patients were detected within the CHG group as 15 (71.4%) before using CHG and as 10 (47.6%) after using (OR: 2.7, p= 0.044, 95% CI: 1.09-2.42). Also, when we compared the control group with the CHG group; there was no significant difference in CRE when comparing the negation rates (p= 0.804). There was a significant difference between the two groups in VRE (p= 0.048).
Conclusion: It shows that performing skin bathing with 2% CHG every other day in the PICU significantly reduces VRE colonization but cannot decrease the risk of CRE colonization. We think that skin bathing with 2% CHG every other day in the PICU can be used as one of the resistant microorganism colonization and infection prevention methods. |
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| ISSN: | 1300-932X 1300-932X |