TprA/PhrA Quorum Sensing System Has a Major Effect on Pneumococcal Survival in Respiratory Tract and Blood, and Its Activity Is Controlled by CcpA and GlnR

TprA/PhrA Quorum Sensing System Has a Major Effect on Pneumococcal Survival in Respiratory Tract and Blood, and Its Activity Is Controlled by CcpA and GlnR

Streptococcus pneumoniae is able to cause deadly diseases by infecting different tissues, each with distinct environmental and nutritional compositions. We hypothesize that the adaptive capabilities of the microbe is an important facet of pneumococcal survival in fluctuating host environments. Quoru...

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Bibliographic Details
Main Authors: Anfal Shakir Motib, Firas A. Y. Al-Bayati, Irfan Manzoor, Sulman Shafeeq, Anagha Kadam, Oscar P. Kuipers, N. Luisa Hiller, Peter W. Andrew, Hasan Yesilkaya
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Streptococcus pneumoniae
transcriptional regulation
TprA/PhrA
sugar metabolism
virulence
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00326/full

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