Detecting Single-Nucleotides by Tunneling Current Measurements at Sub-MHz Temporal Resolution

Detecting Single-Nucleotides by Tunneling Current Measurements at Sub-MHz Temporal Resolution

Label-free detection of single-nucleotides was performed by fast tunneling current measurements in a polar solvent at 1 MHz sampling rate using SiO2-protected Au nanoprobes. Short current spikes were observed, suggestive of trapping/detrapping of individual nucleotides between the nanoelectrodes. Th...

Full description

Bibliographic Details
Main Authors: Takanori Morikawa, Kazumichi Yokota, Sachie Tanimoto, Makusu Tsutsui, Masateru Taniguchi
Format: Article
Language:English
Published: MDPI AG 2017-04-01
Series:Sensors
Subjects:
tunneling current
single molecule
sequencing
Online Access:http://www.mdpi.com/1424-8220/17/4/885

Similar Items

Similar Items