Polysynovitis in a horse due to <i>Borrelia burgdorferi</i> sensu lato infection – Case study
Lyme borreliosis (LB) is a multi-systemic tick-borne disease affecting both humans and animals, including horses, and is caused by a group of interrelated spirochetes classified within the <i>Borrelia burgdorferi</i> sensu lato (s.l.) complex. Despite the high reported seroprevalence in...
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Institute of Rural Health
2015-05-01
|
| Series: | Annals of Agricultural and Environmental Medicine |
| Subjects: | |
| Online Access: | http://www.journalssystem.com/aaem/Polysynovitis-in-a-horse-due-to-i-Borrelia-burgdorferi-i-sensu-lato-infection-Case-study,72268,0,2.html |
| _version_ | 1818131680268910592 |
|---|---|
| author | Fabrizio Passamonti Fabrizia Veronesi Katia Cappelli Stefano Capomaccio Alice Reginato Arianna Miglio Doron M Vardi Valentina Stefanetti Mauro Coletti Chiara Bazzica Marco Pepe |
| author_facet | Fabrizio Passamonti Fabrizia Veronesi Katia Cappelli Stefano Capomaccio Alice Reginato Arianna Miglio Doron M Vardi Valentina Stefanetti Mauro Coletti Chiara Bazzica Marco Pepe |
| author_sort | Fabrizio Passamonti |
| collection | DOAJ |
| description | Lyme borreliosis (LB) is a multi-systemic tick-borne disease affecting both humans and animals, including horses, and is caused by a group of interrelated spirochetes classified within the <i>Borrelia burgdorferi</i> sensu lato (s.l.) complex. Despite the high reported seroprevalence in the European equine population for <i>B. burgdorferi</i> s.l., to-date no documented clinical cases have been described. A 6-year-old Paint gelding was referred with a history of three weeks of fever, intermittent lameness and digital flexor tendon sheath effusion of the right hind limb. Based on a strict diagnostic protocol, which included serological tests for infectious diseases and molecular investigations, a final diagnosis was made of polysynovitis due to <i>B. burgdorferi</i> s.l. infection. An unreported aspect observed in this case was the absence of the pathogen DNA in two of the affected joints. To the authors’ knowledge, the case described represents the first documented clinical case of equine LB in Italy. Moreover, the absence of pathogen DNA in two of the affected joints observed in this case revealed a possible similarity with the same condition described in humans, where an immunomediated pathogenesis for arthropathy due to <i>B. burgdorferi</i> s.l. infection is suspected. Since humans and horses share the same habitat, this report supports the role of the horse as potential sentinel for human biological risk. |
| first_indexed | 2024-12-11T08:24:47Z |
| format | Article |
| id | doaj.art-f6e5f67dead346598b0da136e7a6a07a |
| institution | Directory Open Access Journal |
| issn | 1232-1966 1898-2263 |
| language | English |
| last_indexed | 2024-12-11T08:24:47Z |
| publishDate | 2015-05-01 |
| publisher | Institute of Rural Health |
| record_format | Article |
| series | Annals of Agricultural and Environmental Medicine |
| spelling | doaj.art-f6e5f67dead346598b0da136e7a6a07a2022-12-22T01:14:34ZengInstitute of Rural HealthAnnals of Agricultural and Environmental Medicine1232-19661898-22632015-05-0122224725010.5604/12321966.115207472268Polysynovitis in a horse due to <i>Borrelia burgdorferi</i> sensu lato infection – Case studyFabrizio Passamonti0Fabrizia Veronesi1Katia Cappelli2Stefano Capomaccio3Alice Reginato4Arianna Miglio5Doron M Vardi6Valentina Stefanetti7Mauro Coletti8Chiara Bazzica9Marco Pepe10Centro di Studio del cavallo sportivo, Department of Veterinary Medicine, University of Perugia, ItalyCentro di Studio del cavallo sportivo, Department of Veterinary Medicine, University of Perugia, ItalyCentro di Studio del cavallo sportivo, Department of Veterinary Medicine, University of Perugia, ItalyCentro di Studio del cavallo sportivo, Department of Veterinary Medicine, University of Perugia, ItalyCentro di Studio del cavallo sportivo, Department of Veterinary Medicine, University of Perugia, ItalyCentro di Studio del cavallo sportivo, Department of Veterinary Medicine, University of Perugia, ItalyCentro di Studio del cavallo sportivo, Department of Veterinary Medicine, University of Perugia, ItalyCentro di Studio del cavallo sportivo, Department of Veterinary Medicine, University of Perugia, ItalyCentro di Studio del cavallo sportivo, Department of Veterinary Medicine, University of Perugia, ItalyCentro di Studio del cavallo sportivo, Department of Veterinary Medicine, University of Perugia, ItalyCentro di Studio del cavallo sportivo, Department of Veterinary Medicine, University of Perugia, ItalyLyme borreliosis (LB) is a multi-systemic tick-borne disease affecting both humans and animals, including horses, and is caused by a group of interrelated spirochetes classified within the <i>Borrelia burgdorferi</i> sensu lato (s.l.) complex. Despite the high reported seroprevalence in the European equine population for <i>B. burgdorferi</i> s.l., to-date no documented clinical cases have been described. A 6-year-old Paint gelding was referred with a history of three weeks of fever, intermittent lameness and digital flexor tendon sheath effusion of the right hind limb. Based on a strict diagnostic protocol, which included serological tests for infectious diseases and molecular investigations, a final diagnosis was made of polysynovitis due to <i>B. burgdorferi</i> s.l. infection. An unreported aspect observed in this case was the absence of the pathogen DNA in two of the affected joints. To the authors’ knowledge, the case described represents the first documented clinical case of equine LB in Italy. Moreover, the absence of pathogen DNA in two of the affected joints observed in this case revealed a possible similarity with the same condition described in humans, where an immunomediated pathogenesis for arthropathy due to <i>B. burgdorferi</i> s.l. infection is suspected. Since humans and horses share the same habitat, this report supports the role of the horse as potential sentinel for human biological risk.http://www.journalssystem.com/aaem/Polysynovitis-in-a-horse-due-to-i-Borrelia-burgdorferi-i-sensu-lato-infection-Case-study,72268,0,2.htmlBorrelia burgdorferi sensu latoBorrelia afzeliipolysynovitisequine |
| spellingShingle | Fabrizio Passamonti Fabrizia Veronesi Katia Cappelli Stefano Capomaccio Alice Reginato Arianna Miglio Doron M Vardi Valentina Stefanetti Mauro Coletti Chiara Bazzica Marco Pepe Polysynovitis in a horse due to <i>Borrelia burgdorferi</i> sensu lato infection – Case study Annals of Agricultural and Environmental Medicine Borrelia burgdorferi sensu lato Borrelia afzelii polysynovitis equine |
| title | Polysynovitis in a horse due to <i>Borrelia burgdorferi</i> sensu lato infection – Case study |
| title_full | Polysynovitis in a horse due to <i>Borrelia burgdorferi</i> sensu lato infection – Case study |
| title_fullStr | Polysynovitis in a horse due to <i>Borrelia burgdorferi</i> sensu lato infection – Case study |
| title_full_unstemmed | Polysynovitis in a horse due to <i>Borrelia burgdorferi</i> sensu lato infection – Case study |
| title_short | Polysynovitis in a horse due to <i>Borrelia burgdorferi</i> sensu lato infection – Case study |
| title_sort | polysynovitis in a horse due to i borrelia burgdorferi i sensu lato infection case study |
| topic | Borrelia burgdorferi sensu lato Borrelia afzelii polysynovitis equine |
| url | http://www.journalssystem.com/aaem/Polysynovitis-in-a-horse-due-to-i-Borrelia-burgdorferi-i-sensu-lato-infection-Case-study,72268,0,2.html |
| work_keys_str_mv | AT fabriziopassamonti polysynovitisinahorseduetoiborreliaburgdorferiisensulatoinfectioncasestudy AT fabriziaveronesi polysynovitisinahorseduetoiborreliaburgdorferiisensulatoinfectioncasestudy AT katiacappelli polysynovitisinahorseduetoiborreliaburgdorferiisensulatoinfectioncasestudy AT stefanocapomaccio polysynovitisinahorseduetoiborreliaburgdorferiisensulatoinfectioncasestudy AT alicereginato polysynovitisinahorseduetoiborreliaburgdorferiisensulatoinfectioncasestudy AT ariannamiglio polysynovitisinahorseduetoiborreliaburgdorferiisensulatoinfectioncasestudy AT doronmvardi polysynovitisinahorseduetoiborreliaburgdorferiisensulatoinfectioncasestudy AT valentinastefanetti polysynovitisinahorseduetoiborreliaburgdorferiisensulatoinfectioncasestudy AT maurocoletti polysynovitisinahorseduetoiborreliaburgdorferiisensulatoinfectioncasestudy AT chiarabazzica polysynovitisinahorseduetoiborreliaburgdorferiisensulatoinfectioncasestudy AT marcopepe polysynovitisinahorseduetoiborreliaburgdorferiisensulatoinfectioncasestudy |