An intelligent neural network model to detect red blood cells for various blood structure classification in microscopic medical images

Biomedical image analysis plays a crucial role in enabling high-performing imaging and various clinical applications. For the proper diagnosis of blood diseases related to red blood cells, red blood cells must be accurately identified and categorized. Manual analysis is time-consuming and prone to m...

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Main Authors: Riaz Ullah Khan, Sultan Almakdi, Mohammed Alshehri, Amin Ul Haq, Aman Ullah, Rajesh Kumar
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024021807
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author Riaz Ullah Khan
Sultan Almakdi
Mohammed Alshehri
Amin Ul Haq
Aman Ullah
Rajesh Kumar
author_facet Riaz Ullah Khan
Sultan Almakdi
Mohammed Alshehri
Amin Ul Haq
Aman Ullah
Rajesh Kumar
author_sort Riaz Ullah Khan
collection DOAJ
description Biomedical image analysis plays a crucial role in enabling high-performing imaging and various clinical applications. For the proper diagnosis of blood diseases related to red blood cells, red blood cells must be accurately identified and categorized. Manual analysis is time-consuming and prone to mistakes. Analyzing multi-label samples, which contain clusters of cells, is challenging due to difficulties in separating individual cells, such as touching or overlapping cells. High-performance biomedical imaging and several medical applications are made possible by advanced biosensors. We develop an intelligent neural network model that can automatically identify and categorize red blood cells from microscopic medical images using region-based convolutional neural networks (RCNN) and cutting-edge biosensors. Our model successfully navigates obstacles like touching or overlapping cells and accurately recognizes various blood structures. Additionally, we utilized data augmentation as a pre-processing method on microscopic images to enhance the model's computational efficiency and expand the sample size. To refine the data and eliminate noise from the dataset, we utilized the Radial Gradient Index filtering algorithm for imaging data equalization. We exhibit improved detection accuracy and a reduced model loss rate when using medical imagery datasets to apply our proposed model in comparison to existing ResNet and GoogleNet models. Our model precisely detected red blood cells in a collection of medical images with 99% training accuracy and 91.21% testing accuracy. Our proposed model outperformed earlier models like ResNet-50 and GoogleNet by 10-15%. Our results demonstrated that Artificial intelligence (AI)-assisted automated red blood cell detection has the potential to revolutionize and speed up blood cell analysis, minimizing human error and enabling early illness diagnosis.
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spelling doaj.art-f6e72d62642e4b43bb2da15ce9cfe6d92024-03-09T09:27:22ZengElsevierHeliyon2405-84402024-02-01104e26149An intelligent neural network model to detect red blood cells for various blood structure classification in microscopic medical imagesRiaz Ullah Khan0Sultan Almakdi1Mohammed Alshehri2Amin Ul Haq3Aman Ullah4Rajesh Kumar5Yangtze Delta Region Institute (Huzhou), University of Electronic Science and Technology of China, Huzhou 313001, China; Corresponding author.Department of Computer Science, College of Computer Science and Information systems, Najran University, Najran 55461, Saudi ArabiaDepartment of Computer Science, College of Computer Science and Information systems, Najran University, Najran 55461, Saudi ArabiaSchool of Computer Science and Engineering, University of Electronic Science and Technology of China, Chengdu 611731, ChinaYangtze Delta Region Institute (Huzhou), University of Electronic Science and Technology of China, Huzhou 313001, ChinaYangtze Delta Region Institute (Huzhou), University of Electronic Science and Technology of China, Huzhou 313001, ChinaBiomedical image analysis plays a crucial role in enabling high-performing imaging and various clinical applications. For the proper diagnosis of blood diseases related to red blood cells, red blood cells must be accurately identified and categorized. Manual analysis is time-consuming and prone to mistakes. Analyzing multi-label samples, which contain clusters of cells, is challenging due to difficulties in separating individual cells, such as touching or overlapping cells. High-performance biomedical imaging and several medical applications are made possible by advanced biosensors. We develop an intelligent neural network model that can automatically identify and categorize red blood cells from microscopic medical images using region-based convolutional neural networks (RCNN) and cutting-edge biosensors. Our model successfully navigates obstacles like touching or overlapping cells and accurately recognizes various blood structures. Additionally, we utilized data augmentation as a pre-processing method on microscopic images to enhance the model's computational efficiency and expand the sample size. To refine the data and eliminate noise from the dataset, we utilized the Radial Gradient Index filtering algorithm for imaging data equalization. We exhibit improved detection accuracy and a reduced model loss rate when using medical imagery datasets to apply our proposed model in comparison to existing ResNet and GoogleNet models. Our model precisely detected red blood cells in a collection of medical images with 99% training accuracy and 91.21% testing accuracy. Our proposed model outperformed earlier models like ResNet-50 and GoogleNet by 10-15%. Our results demonstrated that Artificial intelligence (AI)-assisted automated red blood cell detection has the potential to revolutionize and speed up blood cell analysis, minimizing human error and enabling early illness diagnosis.http://www.sciencedirect.com/science/article/pii/S2405844024021807RBC detectionObject detectionImage processingDeep learning
spellingShingle Riaz Ullah Khan
Sultan Almakdi
Mohammed Alshehri
Amin Ul Haq
Aman Ullah
Rajesh Kumar
An intelligent neural network model to detect red blood cells for various blood structure classification in microscopic medical images
Heliyon
RBC detection
Object detection
Image processing
Deep learning
title An intelligent neural network model to detect red blood cells for various blood structure classification in microscopic medical images
title_full An intelligent neural network model to detect red blood cells for various blood structure classification in microscopic medical images
title_fullStr An intelligent neural network model to detect red blood cells for various blood structure classification in microscopic medical images
title_full_unstemmed An intelligent neural network model to detect red blood cells for various blood structure classification in microscopic medical images
title_short An intelligent neural network model to detect red blood cells for various blood structure classification in microscopic medical images
title_sort intelligent neural network model to detect red blood cells for various blood structure classification in microscopic medical images
topic RBC detection
Object detection
Image processing
Deep learning
url http://www.sciencedirect.com/science/article/pii/S2405844024021807
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