Qualitative and Quantitative Determination of Decoquinate in Chicken Tissues by Gas Chromatography Tandem Mass Spectrometry
A novel precolumn derivatization–GC-MS/MS method was developed for the determination of decoquinate residues in chicken tissues (muscle, liver, and kidney). The samples were extracted and purified by liquid–liquid extraction combined with solid-phase extraction and derivatized with acetic anhydride...
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| Format: | Article |
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MDPI AG
2023-05-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/28/9/3875 |
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| author | Shuyu Liu Yayun Tang Yang Lu Yawen Guo Kaizhou Xie Fanxun Guan Pengfei Gao Yali Zhu Yuhao Dong Tao Zhang Genxi Zhang Guojun Dai Xing Xie |
| author_facet | Shuyu Liu Yayun Tang Yang Lu Yawen Guo Kaizhou Xie Fanxun Guan Pengfei Gao Yali Zhu Yuhao Dong Tao Zhang Genxi Zhang Guojun Dai Xing Xie |
| author_sort | Shuyu Liu |
| collection | DOAJ |
| description | A novel precolumn derivatization–GC-MS/MS method was developed for the determination of decoquinate residues in chicken tissues (muscle, liver, and kidney). The samples were extracted and purified by liquid–liquid extraction combined with solid-phase extraction and derivatized with acetic anhydride and pyridine. The recovery rates for decoquinate were 77.38~89.65%, and the intra-day and inter-day RSDs were 1.63~5.74% and 2.27~8.06%, respectively. The technique parameters meet the necessities for veterinary drug residue detection in China, the US, and the EU. Finally, the method was applied to analyze tissues of 60 chickens bought from a neighborhood supermarket, and solely one sample of chicken muscle contained 15.6 μg/kg decoquinate residue. |
| first_indexed | 2024-03-11T04:12:40Z |
| format | Article |
| id | doaj.art-f6e91f21991c42778906e245bbaadb2b |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-11T04:12:40Z |
| publishDate | 2023-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-f6e91f21991c42778906e245bbaadb2b2023-11-17T23:24:39ZengMDPI AGMolecules1420-30492023-05-01289387510.3390/molecules28093875Qualitative and Quantitative Determination of Decoquinate in Chicken Tissues by Gas Chromatography Tandem Mass SpectrometryShuyu Liu0Yayun Tang1Yang Lu2Yawen Guo3Kaizhou Xie4Fanxun Guan5Pengfei Gao6Yali Zhu7Yuhao Dong8Tao Zhang9Genxi Zhang10Guojun Dai11Xing Xie12College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, ChinaCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, ChinaCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, ChinaCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, ChinaCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, ChinaCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, ChinaCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, ChinaCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, ChinaCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, ChinaCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, ChinaCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, ChinaCollege of Animal Science and Technology, Yangzhou University, Yangzhou 225009, ChinaKey Laboratory of Veterinary Biological Engineering and Technology, Institute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences, Ministry of Agriculture, Nanjing 210014, ChinaA novel precolumn derivatization–GC-MS/MS method was developed for the determination of decoquinate residues in chicken tissues (muscle, liver, and kidney). The samples were extracted and purified by liquid–liquid extraction combined with solid-phase extraction and derivatized with acetic anhydride and pyridine. The recovery rates for decoquinate were 77.38~89.65%, and the intra-day and inter-day RSDs were 1.63~5.74% and 2.27~8.06%, respectively. The technique parameters meet the necessities for veterinary drug residue detection in China, the US, and the EU. Finally, the method was applied to analyze tissues of 60 chickens bought from a neighborhood supermarket, and solely one sample of chicken muscle contained 15.6 μg/kg decoquinate residue.https://www.mdpi.com/1420-3049/28/9/3875decoquinategc-ms/msderivatizationchicken tissuesacetic anhydride |
| spellingShingle | Shuyu Liu Yayun Tang Yang Lu Yawen Guo Kaizhou Xie Fanxun Guan Pengfei Gao Yali Zhu Yuhao Dong Tao Zhang Genxi Zhang Guojun Dai Xing Xie Qualitative and Quantitative Determination of Decoquinate in Chicken Tissues by Gas Chromatography Tandem Mass Spectrometry Molecules decoquinate gc-ms/ms derivatization chicken tissues acetic anhydride |
| title | Qualitative and Quantitative Determination of Decoquinate in Chicken Tissues by Gas Chromatography Tandem Mass Spectrometry |
| title_full | Qualitative and Quantitative Determination of Decoquinate in Chicken Tissues by Gas Chromatography Tandem Mass Spectrometry |
| title_fullStr | Qualitative and Quantitative Determination of Decoquinate in Chicken Tissues by Gas Chromatography Tandem Mass Spectrometry |
| title_full_unstemmed | Qualitative and Quantitative Determination of Decoquinate in Chicken Tissues by Gas Chromatography Tandem Mass Spectrometry |
| title_short | Qualitative and Quantitative Determination of Decoquinate in Chicken Tissues by Gas Chromatography Tandem Mass Spectrometry |
| title_sort | qualitative and quantitative determination of decoquinate in chicken tissues by gas chromatography tandem mass spectrometry |
| topic | decoquinate gc-ms/ms derivatization chicken tissues acetic anhydride |
| url | https://www.mdpi.com/1420-3049/28/9/3875 |
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