Dermal Progression of Neonatal Jaundice of Newborn Under 35 Weeks of Gestational Age

Aim:To determine the dermal progression of neonatal jaundice in newborns under 35 weeks of gestational age and those risk factors which affect dermal progression.Materials and Methods:We prospectively enrolled eighty-eight preterm newborns under 35 weeks of gestational age in neonatol intensive care...

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Main Authors: Çisil Çerçi Kubur, Burçin İşcan, Nuray Duman, Hasan Özkan, Abdullah Kumral
Format: Article
Language:English
Published: Galenos Yayinevi 2022-12-01
Series:Journal of Pediatric Research
Subjects:
Online Access: http://jpedres.org/archives/archive-detail/article-preview/dermal-progression-of-neonatal-jaundice-of-newborn/57509
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author Çisil Çerçi Kubur
Burçin İşcan
Nuray Duman
Hasan Özkan
Abdullah Kumral
author_facet Çisil Çerçi Kubur
Burçin İşcan
Nuray Duman
Hasan Özkan
Abdullah Kumral
author_sort Çisil Çerçi Kubur
collection DOAJ
description Aim:To determine the dermal progression of neonatal jaundice in newborns under 35 weeks of gestational age and those risk factors which affect dermal progression.Materials and Methods:We prospectively enrolled eighty-eight preterm newborns under 35 weeks of gestational age in neonatol intensive care unit of Dokuz Eylül University Hospital. It was a cross-sectional analytic case study. We measured capillary and transcutaneous bilirubin levels. Multiple sites of TcB measurement were performed.Results:We observed that there is no significant difference between capillary and transcutaneous bilirubin measurements on preterm newborns under 35 weeks of gestational age (pearson’s rho >75 and p<0.05). Additionally, we also observed that transcutaneous bilirubin measurements on preterm newborns under 35 weeks of gestational age (the first day taken on the back, the fourth day on the forehead and the remaining days on the chest) are higher than on the other sides (Friedman test). Therefore, for preterm newborns, jaundice progresses in a different way to cephalocaudal direction with progressive hyperbilirubinemia. We did not observe any association between the existence of cephalocaudal progression in preterm newborns and the laboratory data associated with the mother and baby (Mann-Whitney U test, p>0.05).Conclusion:Transcutaneous bilirubin measurements can be used for neonatal jaundice of newborns under 35 weeks of gestational age. However, we need further studies for comprehensive descriptions of preterm newborns’ jaundice progression.
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spelling doaj.art-f6f12640fdf54dc499e38be84b8ecfd22023-02-15T16:18:32ZengGalenos YayineviJournal of Pediatric Research2147-94452587-24782022-12-019433834410.4274/jpr.galenos.2022.5665013049054Dermal Progression of Neonatal Jaundice of Newborn Under 35 Weeks of Gestational AgeÇisil Çerçi Kubur0Burçin İşcan1Nuray Duman2Hasan Özkan3Abdullah Kumral4 Dokuz Eylül University Faculty of Medicine, Department of Pediatrics, İzmir, Turkey Dokuz Eylül University Faculty of Medicine, Department of Pediatrics, Division of Neonatology, İzmir, Turkey Dokuz Eylül University Faculty of Medicine, Department of Pediatrics, Division of Neonatology, İzmir, Turkey Dokuz Eylül University Faculty of Medicine, Department of Pediatrics, Division of Neonatology, İzmir, Turkey Dokuz Eylül University Faculty of Medicine, Department of Pediatrics, Division of Neonatology, İzmir, Turkey Aim:To determine the dermal progression of neonatal jaundice in newborns under 35 weeks of gestational age and those risk factors which affect dermal progression.Materials and Methods:We prospectively enrolled eighty-eight preterm newborns under 35 weeks of gestational age in neonatol intensive care unit of Dokuz Eylül University Hospital. It was a cross-sectional analytic case study. We measured capillary and transcutaneous bilirubin levels. Multiple sites of TcB measurement were performed.Results:We observed that there is no significant difference between capillary and transcutaneous bilirubin measurements on preterm newborns under 35 weeks of gestational age (pearson’s rho >75 and p<0.05). Additionally, we also observed that transcutaneous bilirubin measurements on preterm newborns under 35 weeks of gestational age (the first day taken on the back, the fourth day on the forehead and the remaining days on the chest) are higher than on the other sides (Friedman test). Therefore, for preterm newborns, jaundice progresses in a different way to cephalocaudal direction with progressive hyperbilirubinemia. We did not observe any association between the existence of cephalocaudal progression in preterm newborns and the laboratory data associated with the mother and baby (Mann-Whitney U test, p>0.05).Conclusion:Transcutaneous bilirubin measurements can be used for neonatal jaundice of newborns under 35 weeks of gestational age. However, we need further studies for comprehensive descriptions of preterm newborns’ jaundice progression. http://jpedres.org/archives/archive-detail/article-preview/dermal-progression-of-neonatal-jaundice-of-newborn/57509 dermal progressionneonatal jaundicegestational agetranscutaneous bilirubin measurementscephalocaudal progression
spellingShingle Çisil Çerçi Kubur
Burçin İşcan
Nuray Duman
Hasan Özkan
Abdullah Kumral
Dermal Progression of Neonatal Jaundice of Newborn Under 35 Weeks of Gestational Age
Journal of Pediatric Research
dermal progression
neonatal jaundice
gestational age
transcutaneous bilirubin measurements
cephalocaudal progression
title Dermal Progression of Neonatal Jaundice of Newborn Under 35 Weeks of Gestational Age
title_full Dermal Progression of Neonatal Jaundice of Newborn Under 35 Weeks of Gestational Age
title_fullStr Dermal Progression of Neonatal Jaundice of Newborn Under 35 Weeks of Gestational Age
title_full_unstemmed Dermal Progression of Neonatal Jaundice of Newborn Under 35 Weeks of Gestational Age
title_short Dermal Progression of Neonatal Jaundice of Newborn Under 35 Weeks of Gestational Age
title_sort dermal progression of neonatal jaundice of newborn under 35 weeks of gestational age
topic dermal progression
neonatal jaundice
gestational age
transcutaneous bilirubin measurements
cephalocaudal progression
url http://jpedres.org/archives/archive-detail/article-preview/dermal-progression-of-neonatal-jaundice-of-newborn/57509
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AT hasanozkan dermalprogressionofneonataljaundiceofnewbornunder35weeksofgestationalage
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