Prevalence of menstrual irregularities after coronavirus disease 2019 vaccination: A cross-sectional study in the Eastern Province, Saudi Arabia
BACKGROUND: Reports indicate that there are menstrual cycle disturbances following coronavirus disease 2019 (COVID-19) vaccination. The present study explored the prevalence of menstrual irregularities after COVID-19 vaccination and the association of menstrual irregularities with vaccine type, dose...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-01-01
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| Series: | Indian Journal of Community and Family Medicine |
| Subjects: | |
| Online Access: | http://www.jfcmonline.com/article.asp?issn=2230-8229;year=2024;volume=31;issue=1;spage=71;epage=78;aulast=Latif |
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| author | Rabia Latif Deena A Aldossary Najla A Aljabari Saja S Alowaied Latifah A Aljabari Noor J Albash Aseel S Alabdulhadi Nazish Rafique Lubna I Al-Asoom Ayad M Salem |
| author_facet | Rabia Latif Deena A Aldossary Najla A Aljabari Saja S Alowaied Latifah A Aljabari Noor J Albash Aseel S Alabdulhadi Nazish Rafique Lubna I Al-Asoom Ayad M Salem |
| author_sort | Rabia Latif |
| collection | DOAJ |
| description | BACKGROUND: Reports indicate that there are menstrual cycle disturbances following coronavirus disease 2019 (COVID-19) vaccination. The present study explored the prevalence of menstrual irregularities after COVID-19 vaccination and the association of menstrual irregularities with vaccine type, doses, immediate adverse effects, history of COVID-19 infection, and its severity.
MATERIALS AND METHODS: For this cross-sectional study, 406 women of reproductive age completed an online survey about the postvaccine changes in their menstruation (cycle duration, bleeding days, and bleeding amount), COVID-19 vaccine history (doses, type of vaccine, and immediate adverse effects), history of COVID-19 infection, and its severity. Data was analyzed using SPSS; descriptive statistics were computed and Chi-square test, and binary logistic regression analysis were performed.
RESULTS: Of the total 406 women, 45% reported postvaccine changes in their menstrual cycle. The most common menstrual change was increased dysmenorrhea (68%), followed by an increase in the length of the cycle (52%). There was a significant association between postvaccine menstrual changes and the age, marital status, and family history of menstrual irregularities. No association was observed between postvaccine menstrual changes and COVID-19 vaccine-and COVID-19 infection-related variables. As per the best-fit model of our predictors, the odds of having postvaccine menstrual changes were 0.41 times less in “single” women (confidence interval [CI] = 0.26–0.27; P < 0.001) and 1.714 times greater in women who had a “family history of menstrual irregularities” (CI = 1.092–2.690; P = 0.02), respectively.
CONCLUSION: A substantial number of women complained of postvaccine menstrual changes regardless of their age, type of COVID-19 vaccine, doses, immediate adverse effects, and COVID-19 infection history/severity. Being “single” decreased the probability, whereas having a family history of menstrual irregularities increased the probability significantly of having postvaccine menstrual changes. |
| first_indexed | 2024-03-07T22:59:41Z |
| format | Article |
| id | doaj.art-f6f2817525ed4422b02e9edcdc113360 |
| institution | Directory Open Access Journal |
| issn | 2395-2113 |
| language | English |
| last_indexed | 2024-03-07T22:59:41Z |
| publishDate | 2024-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Community and Family Medicine |
| spelling | doaj.art-f6f2817525ed4422b02e9edcdc1133602024-02-22T15:10:04ZengWolters Kluwer Medknow PublicationsIndian Journal of Community and Family Medicine2395-21132024-01-01311717810.4103/jfcm.jfcm_115_23Prevalence of menstrual irregularities after coronavirus disease 2019 vaccination: A cross-sectional study in the Eastern Province, Saudi ArabiaRabia LatifDeena A AldossaryNajla A AljabariSaja S AlowaiedLatifah A AljabariNoor J AlbashAseel S AlabdulhadiNazish RafiqueLubna I Al-AsoomAyad M SalemBACKGROUND: Reports indicate that there are menstrual cycle disturbances following coronavirus disease 2019 (COVID-19) vaccination. The present study explored the prevalence of menstrual irregularities after COVID-19 vaccination and the association of menstrual irregularities with vaccine type, doses, immediate adverse effects, history of COVID-19 infection, and its severity. MATERIALS AND METHODS: For this cross-sectional study, 406 women of reproductive age completed an online survey about the postvaccine changes in their menstruation (cycle duration, bleeding days, and bleeding amount), COVID-19 vaccine history (doses, type of vaccine, and immediate adverse effects), history of COVID-19 infection, and its severity. Data was analyzed using SPSS; descriptive statistics were computed and Chi-square test, and binary logistic regression analysis were performed. RESULTS: Of the total 406 women, 45% reported postvaccine changes in their menstrual cycle. The most common menstrual change was increased dysmenorrhea (68%), followed by an increase in the length of the cycle (52%). There was a significant association between postvaccine menstrual changes and the age, marital status, and family history of menstrual irregularities. No association was observed between postvaccine menstrual changes and COVID-19 vaccine-and COVID-19 infection-related variables. As per the best-fit model of our predictors, the odds of having postvaccine menstrual changes were 0.41 times less in “single” women (confidence interval [CI] = 0.26–0.27; P < 0.001) and 1.714 times greater in women who had a “family history of menstrual irregularities” (CI = 1.092–2.690; P = 0.02), respectively. CONCLUSION: A substantial number of women complained of postvaccine menstrual changes regardless of their age, type of COVID-19 vaccine, doses, immediate adverse effects, and COVID-19 infection history/severity. Being “single” decreased the probability, whereas having a family history of menstrual irregularities increased the probability significantly of having postvaccine menstrual changes.http://www.jfcmonline.com/article.asp?issn=2230-8229;year=2024;volume=31;issue=1;spage=71;epage=78;aulast=Latifcoronavirus disease 2019 vaccinesdysmenorrheamenstrual cyclemenstruation disturbancessars-cov-2 |
| spellingShingle | Rabia Latif Deena A Aldossary Najla A Aljabari Saja S Alowaied Latifah A Aljabari Noor J Albash Aseel S Alabdulhadi Nazish Rafique Lubna I Al-Asoom Ayad M Salem Prevalence of menstrual irregularities after coronavirus disease 2019 vaccination: A cross-sectional study in the Eastern Province, Saudi Arabia Indian Journal of Community and Family Medicine coronavirus disease 2019 vaccines dysmenorrhea menstrual cycle menstruation disturbances sars-cov-2 |
| title | Prevalence of menstrual irregularities after coronavirus disease 2019 vaccination: A cross-sectional study in the Eastern Province, Saudi Arabia |
| title_full | Prevalence of menstrual irregularities after coronavirus disease 2019 vaccination: A cross-sectional study in the Eastern Province, Saudi Arabia |
| title_fullStr | Prevalence of menstrual irregularities after coronavirus disease 2019 vaccination: A cross-sectional study in the Eastern Province, Saudi Arabia |
| title_full_unstemmed | Prevalence of menstrual irregularities after coronavirus disease 2019 vaccination: A cross-sectional study in the Eastern Province, Saudi Arabia |
| title_short | Prevalence of menstrual irregularities after coronavirus disease 2019 vaccination: A cross-sectional study in the Eastern Province, Saudi Arabia |
| title_sort | prevalence of menstrual irregularities after coronavirus disease 2019 vaccination a cross sectional study in the eastern province saudi arabia |
| topic | coronavirus disease 2019 vaccines dysmenorrhea menstrual cycle menstruation disturbances sars-cov-2 |
| url | http://www.jfcmonline.com/article.asp?issn=2230-8229;year=2024;volume=31;issue=1;spage=71;epage=78;aulast=Latif |
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