Complex Vascular Reconstruction following Resection of a Large Retroperitoneal Teratoma
Germ cell tumors (GCTs) are a common malignancy in males, with variations in differentiation making different therapeutic strategies necessary. Generally, GCTs show good curation rates due to their good response to radiotherapy or chemotherapy. However, certain subtypes are resistant to these therap...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-03-01
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| Series: | Surgeries |
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| Online Access: | https://www.mdpi.com/2673-4095/2/2/13 |
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| author | Björn-Ole Stüben Asmus Heumann Anastasios D. Giannou Sabine Wipper Peter Bannas Jun Li |
| author_facet | Björn-Ole Stüben Asmus Heumann Anastasios D. Giannou Sabine Wipper Peter Bannas Jun Li |
| author_sort | Björn-Ole Stüben |
| collection | DOAJ |
| description | Germ cell tumors (GCTs) are a common malignancy in males, with variations in differentiation making different therapeutic strategies necessary. Generally, GCTs show good curation rates due to their good response to radiotherapy or chemotherapy. However, certain subtypes are resistant to these therapies and require surgery. We present a case of a 25-year-old patient with a large retroperitoneal GCT with somatic malignant transformation, where resection of large abdominal blood vessels with complex reconstruction was necessary to completely remove the tumor. The tumor was completely resected, and the patient has since been recurrence-free in the follow-up period. GCTs with somatic transformation show high resistance rates to chemo- and radiotherapy, and the patient in the presented case study did indeed show only a limited response to carboplatin-based chemotherapy. Patients suffering from these conditions should be resected whenever possible, as curation can be achieved by complete tumor resection. Infiltration of neighboring structures is no contraindication to surgery. The case presented here shows that interdisciplinary surgical planning including vascular and general surgeons as well as radiologists is vital to ensure successful tumor resection. |
| first_indexed | 2024-03-10T12:49:53Z |
| format | Article |
| id | doaj.art-f6f6f7bbb0374bf1a0784455407c8e16 |
| institution | Directory Open Access Journal |
| issn | 2673-4095 |
| language | English |
| last_indexed | 2024-03-10T12:49:53Z |
| publishDate | 2021-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Surgeries |
| spelling | doaj.art-f6f6f7bbb0374bf1a0784455407c8e162023-11-21T13:11:42ZengMDPI AGSurgeries2673-40952021-03-012213914310.3390/surgeries2020013Complex Vascular Reconstruction following Resection of a Large Retroperitoneal TeratomaBjörn-Ole Stüben0Asmus Heumann1Anastasios D. Giannou2Sabine Wipper3Peter Bannas4Jun Li5Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, GermanyDepartment of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, GermanyDepartment of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, GermanyDepartment of Vascular Medicine, University Heart & Vascular Center Hamburg-Eppendorf, 20246 Hamburg, GermanyDepartment of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, GermanyDepartment of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, GermanyGerm cell tumors (GCTs) are a common malignancy in males, with variations in differentiation making different therapeutic strategies necessary. Generally, GCTs show good curation rates due to their good response to radiotherapy or chemotherapy. However, certain subtypes are resistant to these therapies and require surgery. We present a case of a 25-year-old patient with a large retroperitoneal GCT with somatic malignant transformation, where resection of large abdominal blood vessels with complex reconstruction was necessary to completely remove the tumor. The tumor was completely resected, and the patient has since been recurrence-free in the follow-up period. GCTs with somatic transformation show high resistance rates to chemo- and radiotherapy, and the patient in the presented case study did indeed show only a limited response to carboplatin-based chemotherapy. Patients suffering from these conditions should be resected whenever possible, as curation can be achieved by complete tumor resection. Infiltration of neighboring structures is no contraindication to surgery. The case presented here shows that interdisciplinary surgical planning including vascular and general surgeons as well as radiologists is vital to ensure successful tumor resection.https://www.mdpi.com/2673-4095/2/2/13germ cell tumormalignant somatic differentiationcomplex vascular reconstruction |
| spellingShingle | Björn-Ole Stüben Asmus Heumann Anastasios D. Giannou Sabine Wipper Peter Bannas Jun Li Complex Vascular Reconstruction following Resection of a Large Retroperitoneal Teratoma Surgeries germ cell tumor malignant somatic differentiation complex vascular reconstruction |
| title | Complex Vascular Reconstruction following Resection of a Large Retroperitoneal Teratoma |
| title_full | Complex Vascular Reconstruction following Resection of a Large Retroperitoneal Teratoma |
| title_fullStr | Complex Vascular Reconstruction following Resection of a Large Retroperitoneal Teratoma |
| title_full_unstemmed | Complex Vascular Reconstruction following Resection of a Large Retroperitoneal Teratoma |
| title_short | Complex Vascular Reconstruction following Resection of a Large Retroperitoneal Teratoma |
| title_sort | complex vascular reconstruction following resection of a large retroperitoneal teratoma |
| topic | germ cell tumor malignant somatic differentiation complex vascular reconstruction |
| url | https://www.mdpi.com/2673-4095/2/2/13 |
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