Role for Galectin‐3 in Calcific Aortic Valve Stenosis

Role for Galectin‐3 in Calcific Aortic Valve Stenosis

BackgroundAortic stenosis (AS) is a chronic inflammatory disease, and calcification plays an important role in the progression of the disease. Galectin‐3 (Gal‐3) is a proinflammatory molecule involved in vascular osteogenesis in atherosclerosis. Therefore, we hypothesized that Gal‐3 could mediate va...

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Bibliographic Details
Main Authors: J. Rafael Sádaba, Ernesto Martínez‐Martínez, Vanessa Arrieta, Virginia Álvarez, Amaya Fernández‐Celis, Jaime Ibarrola, Amaia Melero, Patrick Rossignol, Victoria Cachofeiro, Natalia López‐Andrés
Format: Article
Language:English
Published: Wiley 2016-10-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
aortic stenosis
calcification
galectin‐3
inflammation
valve
valvular interstitial cells
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.116.004360

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