STI prevalence among men living with HIV engaged in safer conception care in rural, southwestern Uganda.
HIV care provides an opportunity to integrate comprehensive sexual and reproductive healthcare, including sexually transmitted infection (STI) management. We describe STI prevalence and correlates among men living with HIV (MLWH) accessing safer conception care to conceive a child with an HIV-uninfe...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2021-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0246629 |
| _version_ | 1818929124231610368 |
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| author | Pooja Chitneni Mwebesa Bosco Bwana Winnie Muyindike Moran Owembabazi Paul Kato Kalyebara Adolf Byamukama Yona Mbalibulha Patricia M Smith Katherine K Hsu Jessica E Haberer Angela Kaida Lynn T Matthews |
| author_facet | Pooja Chitneni Mwebesa Bosco Bwana Winnie Muyindike Moran Owembabazi Paul Kato Kalyebara Adolf Byamukama Yona Mbalibulha Patricia M Smith Katherine K Hsu Jessica E Haberer Angela Kaida Lynn T Matthews |
| author_sort | Pooja Chitneni |
| collection | DOAJ |
| description | HIV care provides an opportunity to integrate comprehensive sexual and reproductive healthcare, including sexually transmitted infection (STI) management. We describe STI prevalence and correlates among men living with HIV (MLWH) accessing safer conception care to conceive a child with an HIV-uninfected partner while minimizing HIV transmission risks. This study reflects an ongoing safer conception program embedded within a regional referral hospital HIV clinic in southwestern Uganda. We enrolled MLWH, planning for pregnancy with an HIV-uninfected partner and accessing safer conception care. Participants completed interviewer-administered questionnaires detailing socio-demographics, gender dynamics, and sexual history. Participants also completed STI laboratory screening for syphilis (immunochromatographic testing confirmed by rapid plasma reagin), and chlamydia, gonorrhea, trichomoniasis, and HIV-RNA via GeneXpert nucleic acid amplification testing. Bivariable associations of STI covariates were assessed using Fisher's exact test. Among the 50 men who completed STI screening, median age was 33 (IQR 31-37) years, 13/50 (26%) had ≥2 sexual partners in the prior three months, and 46/50 (92%) had HIV-RNA <400 copies/mL. Overall, 11/50 (22%) had STIs: 16% active syphilis, 6% chlamydia. All participants initiated STI treatment. STI prevalence was associated with the use of threats/intimidation to coerce partners into sex (27% vs 3%; p = 0.03), although absolute numbers were small. We describe a 22% curable STI prevalence among a priority population at higher risk for transmission to partners and neonates. STI screening and treatment as a part of comprehensive sexual and reproductive healthcare should be integrated into HIV care to maximize the health of men, women, and children. |
| first_indexed | 2024-12-20T03:39:49Z |
| format | Article |
| id | doaj.art-f6fe5795c4c74fa4abf5c07fa84a6955 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-20T03:39:49Z |
| publishDate | 2021-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-f6fe5795c4c74fa4abf5c07fa84a69552022-12-21T19:54:47ZengPublic Library of Science (PLoS)PLoS ONE1932-62032021-01-01163e024662910.1371/journal.pone.0246629STI prevalence among men living with HIV engaged in safer conception care in rural, southwestern Uganda.Pooja ChitneniMwebesa Bosco BwanaWinnie MuyindikeMoran OwembabaziPaul Kato KalyebaraAdolf ByamukamaYona MbalibulhaPatricia M SmithKatherine K HsuJessica E HabererAngela KaidaLynn T MatthewsHIV care provides an opportunity to integrate comprehensive sexual and reproductive healthcare, including sexually transmitted infection (STI) management. We describe STI prevalence and correlates among men living with HIV (MLWH) accessing safer conception care to conceive a child with an HIV-uninfected partner while minimizing HIV transmission risks. This study reflects an ongoing safer conception program embedded within a regional referral hospital HIV clinic in southwestern Uganda. We enrolled MLWH, planning for pregnancy with an HIV-uninfected partner and accessing safer conception care. Participants completed interviewer-administered questionnaires detailing socio-demographics, gender dynamics, and sexual history. Participants also completed STI laboratory screening for syphilis (immunochromatographic testing confirmed by rapid plasma reagin), and chlamydia, gonorrhea, trichomoniasis, and HIV-RNA via GeneXpert nucleic acid amplification testing. Bivariable associations of STI covariates were assessed using Fisher's exact test. Among the 50 men who completed STI screening, median age was 33 (IQR 31-37) years, 13/50 (26%) had ≥2 sexual partners in the prior three months, and 46/50 (92%) had HIV-RNA <400 copies/mL. Overall, 11/50 (22%) had STIs: 16% active syphilis, 6% chlamydia. All participants initiated STI treatment. STI prevalence was associated with the use of threats/intimidation to coerce partners into sex (27% vs 3%; p = 0.03), although absolute numbers were small. We describe a 22% curable STI prevalence among a priority population at higher risk for transmission to partners and neonates. STI screening and treatment as a part of comprehensive sexual and reproductive healthcare should be integrated into HIV care to maximize the health of men, women, and children.https://doi.org/10.1371/journal.pone.0246629 |
| spellingShingle | Pooja Chitneni Mwebesa Bosco Bwana Winnie Muyindike Moran Owembabazi Paul Kato Kalyebara Adolf Byamukama Yona Mbalibulha Patricia M Smith Katherine K Hsu Jessica E Haberer Angela Kaida Lynn T Matthews STI prevalence among men living with HIV engaged in safer conception care in rural, southwestern Uganda. PLoS ONE |
| title | STI prevalence among men living with HIV engaged in safer conception care in rural, southwestern Uganda. |
| title_full | STI prevalence among men living with HIV engaged in safer conception care in rural, southwestern Uganda. |
| title_fullStr | STI prevalence among men living with HIV engaged in safer conception care in rural, southwestern Uganda. |
| title_full_unstemmed | STI prevalence among men living with HIV engaged in safer conception care in rural, southwestern Uganda. |
| title_short | STI prevalence among men living with HIV engaged in safer conception care in rural, southwestern Uganda. |
| title_sort | sti prevalence among men living with hiv engaged in safer conception care in rural southwestern uganda |
| url | https://doi.org/10.1371/journal.pone.0246629 |
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