Resistance training in humans and mechanical overload in rodents do not elevate muscle protein lactylation

Resistance training in humans and mechanical overload in rodents do not elevate muscle protein lactylation

Although several reports have hypothesized that exercise may increase skeletal muscle protein lactylation, empirical evidence in humans is lacking. Thus, we adopted a multi-faceted approach to examine if acute and subchronic resistance training (RT) altered skeletal muscle protein lactylation levels...

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Bibliographic Details
Main Authors: Madison L. Mattingly, Bradley A. Ruple, Casey L. Sexton, Joshua S. Godwin, Mason C. McIntosh, Morgan A. Smith, Daniel L. Plotkin, J. Max Michel, Derick A. Anglin, Nicholas J. Kontos, Shengyi Fei, Stuart M. Phillips, C. Brooks Mobley, Ivan Vechetti, Christopher G. Vann, Michael D. Roberts
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Physiology
Subjects:
skeletal muscle
hypertrophy
lactate
lactylation
posttranslational modification
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1281702/full

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