Maternal heme-enriched diet promotes a gut pro-oxidative status associated with microbiota alteration, gut leakiness and glucose intolerance in mice offspring

Maternal heme-enriched diet promotes a gut pro-oxidative status associated with microbiota alteration, gut leakiness and glucose intolerance in mice offspring

Maternal environment, including nutrition and microbiota, plays a critical role in determining offspring's risk of chronic diseases such as diabetes later in life. Heme iron requirement is amplified during pregnancy and lactation, while excessive dietary heme iron intake, compared to non-heme i...

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Bibliographic Details
Main Authors: Anaïs Mazenc, Loïc Mervant, Claire Maslo, Corinne Lencina, Valérie Bézirard, Mathilde Levêque, Ingrid Ahn, Valérie Alquier-Bacquié, Nathalie Naud, Cécile Héliès-Toussaint, Laurent Debrauwer, Sylvie Chevolleau, Françoise Guéraud, Fabrice H.F. Pierre, Vassilia Théodorou, Maïwenn Olier
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Redox Biology
Subjects:
Heme iron
Early life nutrition
Lipoperoxidation
Red meat
Gut barrier
Gut microbiota
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722001057

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