Detecting key structural features within highly recombined genes.

Many microorganisms exhibit high levels of intragenic recombination following horizontal gene transfer events. Furthermore, many microbial genes are subject to strong diversifying selection as part of the pathogenic process. A multiple sequence alignment is an essential starting point for many of th...

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Bibliographic Details
Main Authors: John E Wertz, Karen F McGregor, Debra E Bessen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1782043?pdf=render