ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilis
The viviparous Great Barrier Reef sponge Luffariella variabilis (Poléjaeff 1884) contains a range of secondary metabolites, including manoalide (1) and manoalide monoacetate (3). ESI (+) FTICR-MS accurate mass determination has, for the first time, been used to detected the presence of 3 only in an...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2010-01-01
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| Series: | Marine Drugs |
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| Online Access: | http://www.mdpi.com/1660-3397/8/1/190/ |
| _version_ | 1811184495295987712 |
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| author | Dianne M. Tapiolas Richard H. Willis Piers Ettinger-Epstein Cherie A. Motti |
| author_facet | Dianne M. Tapiolas Richard H. Willis Piers Ettinger-Epstein Cherie A. Motti |
| author_sort | Dianne M. Tapiolas |
| collection | DOAJ |
| description | The viviparous Great Barrier Reef sponge Luffariella variabilis (Poléjaeff 1884) contains a range of secondary metabolites, including manoalide (1) and manoalide monoacetate (3). ESI (+) FTICR-MS accurate mass determination has, for the first time, been used to detected the presence of 3 only in an organic extract of a single L. variabilis larva showing that the parentally produced 3 is sequestered in the larva. As 3 has previously been shown to have antibacterial and quorum sensing inhibition activity, and readily converts to 1, which also exhibits similar activity, it may provide a chemical defence against predation and microbial attack. |
| first_indexed | 2024-04-11T13:13:12Z |
| format | Article |
| id | doaj.art-f706a3debab24a189e48f0f10fd76f3c |
| institution | Directory Open Access Journal |
| issn | 1660-3397 |
| language | English |
| last_indexed | 2024-04-11T13:13:12Z |
| publishDate | 2010-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Marine Drugs |
| spelling | doaj.art-f706a3debab24a189e48f0f10fd76f3c2022-12-22T04:22:28ZengMDPI AGMarine Drugs1660-33972010-01-018119019910.3390/md8010190ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilisDianne M. TapiolasRichard H. WillisPiers Ettinger-EpsteinCherie A. MottiThe viviparous Great Barrier Reef sponge Luffariella variabilis (Poléjaeff 1884) contains a range of secondary metabolites, including manoalide (1) and manoalide monoacetate (3). ESI (+) FTICR-MS accurate mass determination has, for the first time, been used to detected the presence of 3 only in an organic extract of a single L. variabilis larva showing that the parentally produced 3 is sequestered in the larva. As 3 has previously been shown to have antibacterial and quorum sensing inhibition activity, and readily converts to 1, which also exhibits similar activity, it may provide a chemical defence against predation and microbial attack.http://www.mdpi.com/1660-3397/8/1/190/Luffariella variabilismanoalide monoacetatelarvaeESI FTICR-MSconstitutive defence |
| spellingShingle | Dianne M. Tapiolas Richard H. Willis Piers Ettinger-Epstein Cherie A. Motti ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilis Marine Drugs Luffariella variabilis manoalide monoacetate larvae ESI FTICR-MS constitutive defence |
| title | ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilis |
| title_full | ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilis |
| title_fullStr | ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilis |
| title_full_unstemmed | ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilis |
| title_short | ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilis |
| title_sort | esi fticr ms analysis of larvae from the marine sponge luffariella variabilis |
| topic | Luffariella variabilis manoalide monoacetate larvae ESI FTICR-MS constitutive defence |
| url | http://www.mdpi.com/1660-3397/8/1/190/ |
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