Direct Medical Costs of Tetanus, Dengue, and Sepsis Patients in an Intensive Care Unit in Vietnam
BackgroundCritically ill patients often require complex clinical care by highly trained staff within a specialized intensive care unit (ICU) with advanced equipment. There are currently limited data on the costs of critical care in low-and middle-income countries (LMICs). This study aims to investig...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-06-01
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| Series: | Frontiers in Public Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2022.893200/full |
| _version_ | 1811342805590605824 |
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| author | Trinh Manh Hung Nguyen Van Hao Nguyen Van Hao Lam Minh Yen Angela McBride Angela McBride Vu Quoc Dat H. Rogier van Doorn H. Rogier van Doorn Huynh Thi Loan Nguyen Thanh Phong Martin J. Llewelyn Behzad Nadjm Sophie Yacoub Sophie Yacoub C. Louise Thwaites C. Louise Thwaites Sayem Ahmed Sayem Ahmed Nguyen Van Vinh Chau Hugo C. Turner The Vietnam ICU Translational Applications Laboratory (VITAL) Investigators Dang Phuong Thao Dang Trung Kien Doan Bui Xuan Thy Dong Huu Khanh Trinh Du Hong Duc Ronald Geskus Ho Bich Hai Ho Quang Chanh Ho Van Hien Huynh Trung Trieu Evelyne Kestelyn Le Dinh Van Khoa Le Thanh Phuong Luu Hoai Bao Tran Luu Phuoc An Angela Mcbride Nguyen Lam Vuong Nguyen Quang Huy Nguyen Than Ha Quyen Nguyen Thanh Ngoc Nguyen Thi Giang Nguyen Thi Le Thanh Nguyen Thi Phuong Dung Nguyen Thi Phuong Thao Ninh Thi Thanh Van Phan Nguyen Quoc Khanh Phung Khanh Lam Phung Tran Huy Nhat Guy Thwaites Tran Minh Duc Jennifer Ilo Van Nuil Vu Ngo Thanh Huyen Cao Thi Tam Duong Bich Thuy Ha Thi Hai Duong Ho Dang Trung Nghia Le Buu Chau Le Mau Toan Le Ngoc Minh Thu Le Thi Mai Thao Luong Thi Hue Tai Nguyen Hoan Phu Nguyen Quoc Viet Nguyen Thanh Nguyen Nguyen Thi Kim Anh Nguyen Van Thanh Duoc Pham Kieu Nguyet Oanh Phan Thi Hong Van Phan Tu Qui Phan Vinh Tho Truong Thi Phuong Thao Natasha Ali David Clifton Mike English Shadi Ghiasi Heloise Greeff Jannis Hagenah Ping Lu Jacob McKnight Chris Paton Pantelis Georgiou Bernard Hernandez Perez Kerri Hill-Cawthorne Alison Holmes Stefan Karolcik Damien Ming Nicolas Moser Liane Canas Alberto Gomez Hamideh Kerdegari Marc Modat Reza Razavi Linda Denehy Luigi Pisani Marcus Schultz |
| author_facet | Trinh Manh Hung Nguyen Van Hao Nguyen Van Hao Lam Minh Yen Angela McBride Angela McBride Vu Quoc Dat H. Rogier van Doorn H. Rogier van Doorn Huynh Thi Loan Nguyen Thanh Phong Martin J. Llewelyn Behzad Nadjm Sophie Yacoub Sophie Yacoub C. Louise Thwaites C. Louise Thwaites Sayem Ahmed Sayem Ahmed Nguyen Van Vinh Chau Hugo C. Turner The Vietnam ICU Translational Applications Laboratory (VITAL) Investigators Dang Phuong Thao Dang Trung Kien Doan Bui Xuan Thy Dong Huu Khanh Trinh Du Hong Duc Ronald Geskus Ho Bich Hai Ho Quang Chanh Ho Van Hien Huynh Trung Trieu Evelyne Kestelyn Le Dinh Van Khoa Le Thanh Phuong Luu Hoai Bao Tran Luu Phuoc An Angela Mcbride Nguyen Lam Vuong Nguyen Quang Huy Nguyen Than Ha Quyen Nguyen Thanh Ngoc Nguyen Thi Giang Nguyen Thi Le Thanh Nguyen Thi Phuong Dung Nguyen Thi Phuong Thao Ninh Thi Thanh Van Phan Nguyen Quoc Khanh Phung Khanh Lam Phung Tran Huy Nhat Guy Thwaites Tran Minh Duc Jennifer Ilo Van Nuil Vu Ngo Thanh Huyen Cao Thi Tam Duong Bich Thuy Ha Thi Hai Duong Ho Dang Trung Nghia Le Buu Chau Le Mau Toan Le Ngoc Minh Thu Le Thi Mai Thao Luong Thi Hue Tai Nguyen Hoan Phu Nguyen Quoc Viet Nguyen Thanh Nguyen Nguyen Thi Kim Anh Nguyen Van Thanh Duoc Pham Kieu Nguyet Oanh Phan Thi Hong Van Phan Tu Qui Phan Vinh Tho Truong Thi Phuong Thao Natasha Ali David Clifton Mike English Shadi Ghiasi Heloise Greeff Jannis Hagenah Ping Lu Jacob McKnight Chris Paton Pantelis Georgiou Bernard Hernandez Perez Kerri Hill-Cawthorne Alison Holmes Stefan Karolcik Damien Ming Nicolas Moser Liane Canas Alberto Gomez Hamideh Kerdegari Marc Modat Reza Razavi Linda Denehy Luigi Pisani Marcus Schultz |
| author_sort | Trinh Manh Hung |
| collection | DOAJ |
| description | BackgroundCritically ill patients often require complex clinical care by highly trained staff within a specialized intensive care unit (ICU) with advanced equipment. There are currently limited data on the costs of critical care in low-and middle-income countries (LMICs). This study aims to investigate the direct-medical costs of key infectious disease (tetanus, sepsis, and dengue) patients admitted to ICU in a hospital in Ho Chi Minh City (HCMC), Vietnam, and explores how the costs and cost drivers can vary between the different diseases.MethodsWe calculated the direct medical costs for patients requiring critical care for tetanus, dengue and sepsis. Costing data (stratified into different cost categories) were extracted from the bills of patients hospitalized to the adult ICU with a dengue, sepsis and tetanus diagnosis that were enrolled in three studies conducted at the Hospital for Tropical Diseases in HCMC from January 2017 to December 2019. The costs were considered from the health sector perspective. The total sample size in this study was 342 patients.ResultsICU care was associated with significant direct medical costs. For patients that did not require mechanical ventilation, the median total ICU cost per patient varied between US$64.40 and US$675 for the different diseases. The costs were higher for patients that required mechanical ventilation, with the median total ICU cost per patient for the different diseases varying between US$2,590 and US$4,250. The main cost drivers varied according to disease and associated severity.ConclusionThis study demonstrates the notable cost of ICU care in Vietnam and in similar LMIC settings. Future studies are needed to further evaluate the costs and economic burden incurred by ICU patients. The data also highlight the importance of evaluating novel critical care interventions that could reduce the costs of ICU care. |
| first_indexed | 2024-04-13T19:18:34Z |
| format | Article |
| id | doaj.art-f7077071376a4b659d7c43626ab987a1 |
| institution | Directory Open Access Journal |
| issn | 2296-2565 |
| language | English |
| last_indexed | 2024-04-13T19:18:34Z |
| publishDate | 2022-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj.art-f7077071376a4b659d7c43626ab987a12022-12-22T02:33:37ZengFrontiers Media S.A.Frontiers in Public Health2296-25652022-06-011010.3389/fpubh.2022.893200893200Direct Medical Costs of Tetanus, Dengue, and Sepsis Patients in an Intensive Care Unit in VietnamTrinh Manh Hung0Nguyen Van Hao1Nguyen Van Hao2Lam Minh Yen3Angela McBride4Angela McBride5Vu Quoc Dat6H. Rogier van Doorn7H. Rogier van Doorn8Huynh Thi Loan9Nguyen Thanh Phong10Martin J. Llewelyn11Behzad Nadjm12Sophie Yacoub13Sophie Yacoub14C. Louise Thwaites15C. Louise Thwaites16Sayem Ahmed17Sayem Ahmed18Nguyen Van Vinh Chau19Hugo C. Turner20The Vietnam ICU Translational Applications Laboratory (VITAL) InvestigatorsDang Phuong ThaoDang Trung KienDoan Bui Xuan ThyDong Huu Khanh TrinhDu Hong DucRonald GeskusHo Bich HaiHo Quang ChanhHo Van HienHuynh Trung TrieuEvelyne KestelynLe Dinh Van KhoaLe Thanh PhuongLuu Hoai Bao TranLuu Phuoc AnAngela McbrideNguyen Lam VuongNguyen Quang HuyNguyen Than Ha QuyenNguyen Thanh NgocNguyen Thi GiangNguyen Thi Le ThanhNguyen Thi Phuong DungNguyen Thi Phuong ThaoNinh Thi Thanh VanPhan Nguyen Quoc KhanhPhung Khanh LamPhung Tran Huy NhatGuy ThwaitesTran Minh DucJennifer Ilo Van NuilVu Ngo Thanh HuyenCao Thi TamDuong Bich ThuyHa Thi Hai DuongHo Dang Trung NghiaLe Buu ChauLe Mau ToanLe Ngoc Minh ThuLe Thi Mai ThaoLuong Thi Hue TaiNguyen Hoan PhuNguyen Quoc VietNguyen Thanh NguyenNguyen Thi Kim AnhNguyen Van Thanh DuocPham Kieu Nguyet OanhPhan Thi Hong VanPhan Tu QuiPhan Vinh ThoTruong Thi Phuong ThaoNatasha AliDavid CliftonMike EnglishShadi GhiasiHeloise GreeffJannis HagenahPing LuJacob McKnightChris PatonPantelis GeorgiouBernard Hernandez PerezKerri Hill-CawthorneAlison HolmesStefan KarolcikDamien MingNicolas MoserLiane CanasAlberto GomezHamideh KerdegariMarc ModatReza RazaviLinda DenehyLuigi PisaniMarcus SchultzOxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, Ho Chi Minh City, VietnamHospital for Tropical Diseases, Ho Chi Minh City, VietnamDepartment of Infectious Diseases, University of Medicine and Pharmacy, Ho Chi Minh City, VietnamOxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, Ho Chi Minh City, VietnamOxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, Ho Chi Minh City, VietnamDepartment of Global Health and Infection, Brighton and Sussex Medical School, Brighton, United KingdomDepartment of Infectious Diseases, Hanoi Medical University, Hanoi, VietnamOxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, Hanoi, VietnamCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United KingdomHospital for Tropical Diseases, Ho Chi Minh City, VietnamHospital for Tropical Diseases, Ho Chi Minh City, VietnamDepartment of Global Health and Infection, Brighton and Sussex Medical School, Brighton, United KingdomMedical Research Council (MRC) Unit the Gambia at the London School of Hygiene & Tropical Medicine, Fajara, GambiaOxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, Ho Chi Minh City, VietnamCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United KingdomOxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, Ho Chi Minh City, VietnamCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United KingdomOxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, Ho Chi Minh City, VietnamCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United KingdomHospital for Tropical Diseases, Ho Chi Minh City, VietnamMRC Centre for Global Infectious Disease Analysis, School of Public Health, Imperial College London, Norfolk Place, London, United KingdomBackgroundCritically ill patients often require complex clinical care by highly trained staff within a specialized intensive care unit (ICU) with advanced equipment. There are currently limited data on the costs of critical care in low-and middle-income countries (LMICs). This study aims to investigate the direct-medical costs of key infectious disease (tetanus, sepsis, and dengue) patients admitted to ICU in a hospital in Ho Chi Minh City (HCMC), Vietnam, and explores how the costs and cost drivers can vary between the different diseases.MethodsWe calculated the direct medical costs for patients requiring critical care for tetanus, dengue and sepsis. Costing data (stratified into different cost categories) were extracted from the bills of patients hospitalized to the adult ICU with a dengue, sepsis and tetanus diagnosis that were enrolled in three studies conducted at the Hospital for Tropical Diseases in HCMC from January 2017 to December 2019. The costs were considered from the health sector perspective. The total sample size in this study was 342 patients.ResultsICU care was associated with significant direct medical costs. For patients that did not require mechanical ventilation, the median total ICU cost per patient varied between US$64.40 and US$675 for the different diseases. The costs were higher for patients that required mechanical ventilation, with the median total ICU cost per patient for the different diseases varying between US$2,590 and US$4,250. The main cost drivers varied according to disease and associated severity.ConclusionThis study demonstrates the notable cost of ICU care in Vietnam and in similar LMIC settings. Future studies are needed to further evaluate the costs and economic burden incurred by ICU patients. The data also highlight the importance of evaluating novel critical care interventions that could reduce the costs of ICU care.https://www.frontiersin.org/articles/10.3389/fpubh.2022.893200/fulldenguesepsistetanusdirect medical costICUVietnam |
| spellingShingle | Trinh Manh Hung Nguyen Van Hao Nguyen Van Hao Lam Minh Yen Angela McBride Angela McBride Vu Quoc Dat H. Rogier van Doorn H. Rogier van Doorn Huynh Thi Loan Nguyen Thanh Phong Martin J. Llewelyn Behzad Nadjm Sophie Yacoub Sophie Yacoub C. Louise Thwaites C. Louise Thwaites Sayem Ahmed Sayem Ahmed Nguyen Van Vinh Chau Hugo C. Turner The Vietnam ICU Translational Applications Laboratory (VITAL) Investigators Dang Phuong Thao Dang Trung Kien Doan Bui Xuan Thy Dong Huu Khanh Trinh Du Hong Duc Ronald Geskus Ho Bich Hai Ho Quang Chanh Ho Van Hien Huynh Trung Trieu Evelyne Kestelyn Le Dinh Van Khoa Le Thanh Phuong Luu Hoai Bao Tran Luu Phuoc An Angela Mcbride Nguyen Lam Vuong Nguyen Quang Huy Nguyen Than Ha Quyen Nguyen Thanh Ngoc Nguyen Thi Giang Nguyen Thi Le Thanh Nguyen Thi Phuong Dung Nguyen Thi Phuong Thao Ninh Thi Thanh Van Phan Nguyen Quoc Khanh Phung Khanh Lam Phung Tran Huy Nhat Guy Thwaites Tran Minh Duc Jennifer Ilo Van Nuil Vu Ngo Thanh Huyen Cao Thi Tam Duong Bich Thuy Ha Thi Hai Duong Ho Dang Trung Nghia Le Buu Chau Le Mau Toan Le Ngoc Minh Thu Le Thi Mai Thao Luong Thi Hue Tai Nguyen Hoan Phu Nguyen Quoc Viet Nguyen Thanh Nguyen Nguyen Thi Kim Anh Nguyen Van Thanh Duoc Pham Kieu Nguyet Oanh Phan Thi Hong Van Phan Tu Qui Phan Vinh Tho Truong Thi Phuong Thao Natasha Ali David Clifton Mike English Shadi Ghiasi Heloise Greeff Jannis Hagenah Ping Lu Jacob McKnight Chris Paton Pantelis Georgiou Bernard Hernandez Perez Kerri Hill-Cawthorne Alison Holmes Stefan Karolcik Damien Ming Nicolas Moser Liane Canas Alberto Gomez Hamideh Kerdegari Marc Modat Reza Razavi Linda Denehy Luigi Pisani Marcus Schultz Direct Medical Costs of Tetanus, Dengue, and Sepsis Patients in an Intensive Care Unit in Vietnam Frontiers in Public Health dengue sepsis tetanus direct medical cost ICU Vietnam |
| title | Direct Medical Costs of Tetanus, Dengue, and Sepsis Patients in an Intensive Care Unit in Vietnam |
| title_full | Direct Medical Costs of Tetanus, Dengue, and Sepsis Patients in an Intensive Care Unit in Vietnam |
| title_fullStr | Direct Medical Costs of Tetanus, Dengue, and Sepsis Patients in an Intensive Care Unit in Vietnam |
| title_full_unstemmed | Direct Medical Costs of Tetanus, Dengue, and Sepsis Patients in an Intensive Care Unit in Vietnam |
| title_short | Direct Medical Costs of Tetanus, Dengue, and Sepsis Patients in an Intensive Care Unit in Vietnam |
| title_sort | direct medical costs of tetanus dengue and sepsis patients in an intensive care unit in vietnam |
| topic | dengue sepsis tetanus direct medical cost ICU Vietnam |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2022.893200/full |
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