Comparison of time consumption and success rate between CT angiography- and CT perfusion- based imaging assessment strategy for the patients with acute ischemic stroke
Abstract Background Our study aimed to compare the time consumption and success rate between CTA- and CTP- based assessment strategy, and to clarify the risk factors associated with the CTP scan failure. Methods Clinical and radiological data of 437 consecutive AIS patients who underwent multiphase...
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| Format: | Article |
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BMC
2022-08-01
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| Series: | BMC Medical Imaging |
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| Online Access: | https://doi.org/10.1186/s12880-022-00880-9 |
| _version_ | 1828144397398573056 |
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| author | Yue Chu Gao Ma Xiao-Quan Xu Shan-Shan Lu Hai-Bin Shi Sheng Liu Qiang-Hui Liu Fei-Yun Wu |
| author_facet | Yue Chu Gao Ma Xiao-Quan Xu Shan-Shan Lu Hai-Bin Shi Sheng Liu Qiang-Hui Liu Fei-Yun Wu |
| author_sort | Yue Chu |
| collection | DOAJ |
| description | Abstract Background Our study aimed to compare the time consumption and success rate between CTA- and CTP- based assessment strategy, and to clarify the risk factors associated with the CTP scan failure. Methods Clinical and radiological data of 437 consecutive AIS patients who underwent multiphase CTA or CTP for pre-treatment evaluation were retrospectively enrolled (CTA group, n = 302; CTP group, n = 135). Time consumption and success rate of CTA- and CTP- based assessment strategy were compared using Mann–Whitney U test and Chi-Squared Test. Univariate analysis and receiver operating curve analysis were used to clarify the risk factors, and their performance in predicting the CTP scan failure. Results Time consumption of CTP scan and reconstruction was significantly longer than that of CTA [775 s vs 263.5 s, P < 0.001]. CTP scan showed significantly higher failure rate than CTA (11% vs 1%, P < 0.001). Severe motion was the most common cause of CTP failure (n = 12, 80%). Baseline National Institute of Health Stroke Scale (NIHSS) score in CTP failure group was significantly higher than that in CTP success group [17 vs 13, P = 0.007]. Baseline NIHSS score of 11 was the optimal threshold value to predict CTP failure with an area under the curve of 0.715, a sensitivity of 86.7%, and a specificity of 45.0%. Conclusions CTP- based strategy showed longer time consumption and higher failure rate than CTA- based strategy. High baseline NIHSS score was significantly associated with CTP scan failure in AIS patients. |
| first_indexed | 2024-04-11T20:14:17Z |
| format | Article |
| id | doaj.art-f70bb6e10bf74f8dac4b160d410d4cf1 |
| institution | Directory Open Access Journal |
| issn | 1471-2342 |
| language | English |
| last_indexed | 2024-04-11T20:14:17Z |
| publishDate | 2022-08-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Medical Imaging |
| spelling | doaj.art-f70bb6e10bf74f8dac4b160d410d4cf12022-12-22T04:05:01ZengBMCBMC Medical Imaging1471-23422022-08-012211810.1186/s12880-022-00880-9Comparison of time consumption and success rate between CT angiography- and CT perfusion- based imaging assessment strategy for the patients with acute ischemic strokeYue Chu0Gao Ma1Xiao-Quan Xu2Shan-Shan Lu3Hai-Bin Shi4Sheng Liu5Qiang-Hui Liu6Fei-Yun Wu7Department of Radiology, First Affiliated Hospital of Nanjing Medical UniversityDepartment of Radiology, First Affiliated Hospital of Nanjing Medical UniversityDepartment of Radiology, First Affiliated Hospital of Nanjing Medical UniversityDepartment of Radiology, First Affiliated Hospital of Nanjing Medical UniversityDepartment of Interventional Radiology, First Affiliated Hospital of Nanjing Medical UniversityDepartment of Interventional Radiology, First Affiliated Hospital of Nanjing Medical UniversityDepartment of Emergency, First Affiliated Hospital of Nanjing Medical UniversityDepartment of Radiology, First Affiliated Hospital of Nanjing Medical UniversityAbstract Background Our study aimed to compare the time consumption and success rate between CTA- and CTP- based assessment strategy, and to clarify the risk factors associated with the CTP scan failure. Methods Clinical and radiological data of 437 consecutive AIS patients who underwent multiphase CTA or CTP for pre-treatment evaluation were retrospectively enrolled (CTA group, n = 302; CTP group, n = 135). Time consumption and success rate of CTA- and CTP- based assessment strategy were compared using Mann–Whitney U test and Chi-Squared Test. Univariate analysis and receiver operating curve analysis were used to clarify the risk factors, and their performance in predicting the CTP scan failure. Results Time consumption of CTP scan and reconstruction was significantly longer than that of CTA [775 s vs 263.5 s, P < 0.001]. CTP scan showed significantly higher failure rate than CTA (11% vs 1%, P < 0.001). Severe motion was the most common cause of CTP failure (n = 12, 80%). Baseline National Institute of Health Stroke Scale (NIHSS) score in CTP failure group was significantly higher than that in CTP success group [17 vs 13, P = 0.007]. Baseline NIHSS score of 11 was the optimal threshold value to predict CTP failure with an area under the curve of 0.715, a sensitivity of 86.7%, and a specificity of 45.0%. Conclusions CTP- based strategy showed longer time consumption and higher failure rate than CTA- based strategy. High baseline NIHSS score was significantly associated with CTP scan failure in AIS patients.https://doi.org/10.1186/s12880-022-00880-9Acute ischemic strokePerfusionAngiographyTime consumptionSuccess rate |
| spellingShingle | Yue Chu Gao Ma Xiao-Quan Xu Shan-Shan Lu Hai-Bin Shi Sheng Liu Qiang-Hui Liu Fei-Yun Wu Comparison of time consumption and success rate between CT angiography- and CT perfusion- based imaging assessment strategy for the patients with acute ischemic stroke BMC Medical Imaging Acute ischemic stroke Perfusion Angiography Time consumption Success rate |
| title | Comparison of time consumption and success rate between CT angiography- and CT perfusion- based imaging assessment strategy for the patients with acute ischemic stroke |
| title_full | Comparison of time consumption and success rate between CT angiography- and CT perfusion- based imaging assessment strategy for the patients with acute ischemic stroke |
| title_fullStr | Comparison of time consumption and success rate between CT angiography- and CT perfusion- based imaging assessment strategy for the patients with acute ischemic stroke |
| title_full_unstemmed | Comparison of time consumption and success rate between CT angiography- and CT perfusion- based imaging assessment strategy for the patients with acute ischemic stroke |
| title_short | Comparison of time consumption and success rate between CT angiography- and CT perfusion- based imaging assessment strategy for the patients with acute ischemic stroke |
| title_sort | comparison of time consumption and success rate between ct angiography and ct perfusion based imaging assessment strategy for the patients with acute ischemic stroke |
| topic | Acute ischemic stroke Perfusion Angiography Time consumption Success rate |
| url | https://doi.org/10.1186/s12880-022-00880-9 |
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