Anti-tumour effects of antimicrobial peptides, components of the innate immune system, against haematopoietic tumours in Drosophila mxc mutants

Anti-tumour effects of antimicrobial peptides, components of the innate immune system, against haematopoietic tumours in Drosophila mxc mutants

The innate immune response is the first line of defence against microbial infections. In Drosophila, two major pathways of the innate immune system (the Toll- and Imd-mediated pathways) induce the synthesis of antimicrobial peptides (AMPs) within the fat body. Recently, it has been reported that cer...

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Bibliographic Details
Main Authors: Mayo Araki, Massanori Kurihara, Suzuko Kinoshita, Rie Awane, Tetsuya Sato, Yasuyuki Ohkawa, Yoshihiro H. Inoue
Format: Article
Language:English
Published: The Company of Biologists 2019-06-01
Series:Disease Models & Mechanisms
Subjects:
Drosophila
Innate immunity
AMPs
Lymph gland
Fat body
Cytotoxicity
Online Access:http://dmm.biologists.org/content/12/6/dmm037721

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