Structural Polymorphism of Guanine Quadruplex-Containing Regions in Human Promoters

Structural Polymorphism of Guanine Quadruplex-Containing Regions in Human Promoters

Intramolecular guanine quadruplexes (G4s) are non-canonical nucleic acid structures formed by four guanine (G)-rich tracts that assemble into a core of stacked planar tetrads. G4-forming DNA sequences are enriched in gene promoters and are implicated in the control of gene expression. Most G4-formin...

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Bibliographic Details
Main Authors:	Christopher Hennecker, Lynn Yamout, Chuyang Zhang, Chenzhi Zhao, David Hiraki, Nicolas Moitessier, Anthony Mittermaier
Format:	Article
Language:	English
Published:	MDPI AG 2022-12-01
Series:	International Journal of Molecular Sciences
Subjects:	G4 G4CR bioinformatics transcription start site TSS
Online Access:	https://www.mdpi.com/1422-0067/23/24/16020

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