Short-Chain Fatty Acids Attenuate Renal Fibrosis and Enhance Autophagy of Renal Tubular Cells in Diabetic Mice Through the HDAC2/ULK1 Axis

Short-Chain Fatty Acids Attenuate Renal Fibrosis and Enhance Autophagy of Renal Tubular Cells in Diabetic Mice Through the HDAC2/ULK1 Axis

Background This study investigated the effect of short-chain fatty acids (SCFAs) on diabetes in a mouse model. Methods Autophagy in Akita mice and streptozocin (STZ)-induced diabetic C57BL/6 mice was determined by Western blots and immunohistochemistry (IHC). Western blots, IHC, hematoxylin and eosi...

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Bibliographic Details
Main Authors: Xiaoying Ma, Qiong Wang
Format: Article
Language:English
Published: Korean Endocrine Society 2022-06-01
Series:Endocrinology and Metabolism
Subjects:
diabetes
diabetic nephropathies
fatty acids, volatile
autophagy
renal fibrosis
Online Access:http://www.e-enm.org/upload/pdf/enm-2021-1336.pdf

Internet

http://www.e-enm.org/upload/pdf/enm-2021-1336.pdf

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