Selective translational usage of TSS and core promoters revealed by translatome sequencing

Selective translational usage of TSS and core promoters revealed by translatome sequencing

Abstract Background In mammals, fine-tuned regulation of gene expression leads to transcription initiation from diverse transcription start sites (TSSs) and multiple core promoters. Although polysome association is a critical step in translation, whether polysome selectively uses TSSs and core promo...

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Bibliographic Details
Main Authors: Hua Li, Ling Bai, Hongmei Li, Xinhui Li, Yani Kang, Ningbo Zhang, Jielin Sun, Zhifeng Shao
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Genomics
Subjects:
CAGE
Translatome sequencing
TSS profiling
Core promoter
Polysome selection
Online Access:http://link.springer.com/article/10.1186/s12864-019-5650-0

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