Artificial RNA Motifs Expand the Programmable Assembly between RNA Modules of a Bimolecular Ribozyme Leading to Application to RNA Nanostructure Design

Artificial RNA Motifs Expand the Programmable Assembly between RNA Modules of a Bimolecular Ribozyme Leading to Application to RNA Nanostructure Design

A bimolecular ribozyme consisting of a core ribozyme (ΔP5 RNA) and an activator module (P5abc RNA) has been used as a platform to design assembled RNA nanostructures. The tight and specific assembly between the P5abc and ΔP5 modules depends on two sets of intermodule interactions. The interface betw...

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Bibliographic Details
Main Authors: Md. Motiar Rahman, Shigeyoshi Matsumura, Yoshiya Ikawa
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Biology
Subjects:
catalytic RNA
group I intron
ribozyme
RNA nanostructure
RNA nanotechnology
Online Access:https://www.mdpi.com/2079-7737/6/4/37

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