Trends in hepatitis B notification rates in Guangzhou, China, between 2009 and 2020: an epidemiological study
Abstract Background Although the prevalence of hepatitis B in Guangzhou, China, is high, the epidemiological trends are not well-documented. We aimed to analyse newly reported hepatitis B cases in Guangzhou between 2009 and 2020 to explore the epidemiological trends and provide insights for the deve...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-12-01
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| Series: | BMC Infectious Diseases |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12879-022-07690-y |
| _version_ | 1811302403207593984 |
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| author | Wei Liu Zhiqiang Dong Wensui Hu Ke Li Lili Sun Jianrong Hou Shijie Jia Yuan Liu |
| author_facet | Wei Liu Zhiqiang Dong Wensui Hu Ke Li Lili Sun Jianrong Hou Shijie Jia Yuan Liu |
| author_sort | Wei Liu |
| collection | DOAJ |
| description | Abstract Background Although the prevalence of hepatitis B in Guangzhou, China, is high, the epidemiological trends are not well-documented. We aimed to analyse newly reported hepatitis B cases in Guangzhou between 2009 and 2020 to explore the epidemiological trends and provide insights for the development of control measures. Methods Information on the population and new cases of hepatitis B in Guangzhou between 2009 and 2020 was obtained from the China Information System for Disease Control and Prevention, which was used to calculate the annual notification rates of hepatitis B by sex, age group (0–9; 10–19; 20–29; 30–39; 40–49; 50–59; ≥ 60 years), and location (urban or rural). Joinpoint regression analysis was used to analyse the temporal trends and calculate the average annual percentage change (AAPC) and annual percentage change (APC) for each identified trend line segment. Results Between 2009 and 2020, 287,034 new cases of hepatitis B were cumulatively reported. The average annual notification rate was 181.13/100,000, and the notification rate showed a long-term downward trend during the period 2009–2020, with an annual decrease of 6.30% (APC − 6.30%; 95% CI − 7.56 to − 5.02%). Men had a significantly higher notification rate than women; however, the sex ratio decreased from a maximum of 2.34 in 2010 to a minimum of 1.54 in 2020. A downward trend in the notification rate was observed in urban areas and an upward trend was observed in rural areas, with an increase in the rural/urban ratio from 0.46 in 2012 to 1.57 in 2020. The notification rate for all age groups showed a decreasing trend from 2009, with the exception of the 50–59 years and ≥ 60 years groups, whose notification rates began to decrease from 2014 and 2015, respectively. Conclusions Although the overall notification rate of hepatitis B in Guangzhou decreased annually, it remained high. Further, in rural areas, the notification rate has been increasing, and effective measures should be taken to control hepatitis B infection in Guangzhou. |
| first_indexed | 2024-04-13T07:27:27Z |
| format | Article |
| id | doaj.art-f71be955a89f4821becc7362b40238f6 |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-04-13T07:27:27Z |
| publishDate | 2022-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-f71be955a89f4821becc7362b40238f62022-12-22T02:56:26ZengBMCBMC Infectious Diseases1471-23342022-12-012211810.1186/s12879-022-07690-yTrends in hepatitis B notification rates in Guangzhou, China, between 2009 and 2020: an epidemiological studyWei Liu0Zhiqiang Dong1Wensui Hu2Ke Li3Lili Sun4Jianrong Hou5Shijie Jia6Yuan Liu7Operations Management Section, Guangzhou Center for Disease Control and PreventionOperations Management Section, Guangzhou Center for Disease Control and PreventionOperations Management Section, Guangzhou Center for Disease Control and PreventionOperations Management Section, Guangzhou Center for Disease Control and PreventionOperations Management Section, Guangzhou Center for Disease Control and PreventionOperations Management Section, Guangzhou Center for Disease Control and PreventionDepartment of Traditional Chinese Medicine, Guangzhou Eighth People’s Hospital Guangzhou Medical UniversityOperations Management Section, Guangzhou Center for Disease Control and PreventionAbstract Background Although the prevalence of hepatitis B in Guangzhou, China, is high, the epidemiological trends are not well-documented. We aimed to analyse newly reported hepatitis B cases in Guangzhou between 2009 and 2020 to explore the epidemiological trends and provide insights for the development of control measures. Methods Information on the population and new cases of hepatitis B in Guangzhou between 2009 and 2020 was obtained from the China Information System for Disease Control and Prevention, which was used to calculate the annual notification rates of hepatitis B by sex, age group (0–9; 10–19; 20–29; 30–39; 40–49; 50–59; ≥ 60 years), and location (urban or rural). Joinpoint regression analysis was used to analyse the temporal trends and calculate the average annual percentage change (AAPC) and annual percentage change (APC) for each identified trend line segment. Results Between 2009 and 2020, 287,034 new cases of hepatitis B were cumulatively reported. The average annual notification rate was 181.13/100,000, and the notification rate showed a long-term downward trend during the period 2009–2020, with an annual decrease of 6.30% (APC − 6.30%; 95% CI − 7.56 to − 5.02%). Men had a significantly higher notification rate than women; however, the sex ratio decreased from a maximum of 2.34 in 2010 to a minimum of 1.54 in 2020. A downward trend in the notification rate was observed in urban areas and an upward trend was observed in rural areas, with an increase in the rural/urban ratio from 0.46 in 2012 to 1.57 in 2020. The notification rate for all age groups showed a decreasing trend from 2009, with the exception of the 50–59 years and ≥ 60 years groups, whose notification rates began to decrease from 2014 and 2015, respectively. Conclusions Although the overall notification rate of hepatitis B in Guangzhou decreased annually, it remained high. Further, in rural areas, the notification rate has been increasing, and effective measures should be taken to control hepatitis B infection in Guangzhou.https://doi.org/10.1186/s12879-022-07690-yHepatitis BEpidemiologyTemporal trendsJoinpoint regression |
| spellingShingle | Wei Liu Zhiqiang Dong Wensui Hu Ke Li Lili Sun Jianrong Hou Shijie Jia Yuan Liu Trends in hepatitis B notification rates in Guangzhou, China, between 2009 and 2020: an epidemiological study BMC Infectious Diseases Hepatitis B Epidemiology Temporal trends Joinpoint regression |
| title | Trends in hepatitis B notification rates in Guangzhou, China, between 2009 and 2020: an epidemiological study |
| title_full | Trends in hepatitis B notification rates in Guangzhou, China, between 2009 and 2020: an epidemiological study |
| title_fullStr | Trends in hepatitis B notification rates in Guangzhou, China, between 2009 and 2020: an epidemiological study |
| title_full_unstemmed | Trends in hepatitis B notification rates in Guangzhou, China, between 2009 and 2020: an epidemiological study |
| title_short | Trends in hepatitis B notification rates in Guangzhou, China, between 2009 and 2020: an epidemiological study |
| title_sort | trends in hepatitis b notification rates in guangzhou china between 2009 and 2020 an epidemiological study |
| topic | Hepatitis B Epidemiology Temporal trends Joinpoint regression |
| url | https://doi.org/10.1186/s12879-022-07690-y |
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