QNBC Is Associated with High Genomic Instability Characterized by Copy Number Alterations and miRNA Deregulation

QNBC Is Associated with High Genomic Instability Characterized by Copy Number Alterations and miRNA Deregulation

Triple-negative breast cancer (TNBC) can be further classified into androgen receptor (AR)-positive TNBC and AR-negative TNBC or quadruple-negative breast cancer (QNBC). Here, we investigated genomic instability in 53 clinical cases by array-CGH and miRNA expression profiling. Immunohistochemical an...

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Bibliographic Details
Main Authors: Shristi Bhattarai, Bruna M. Sugita, Stefanne M. Bortoletto, Aline S. Fonseca, Luciane R. Cavalli, Ritu Aneja
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
triple-negative breast cancer
quadruple-negative breast cancer
AR loss
genomic instability
copy number
array-CGH
Online Access:https://www.mdpi.com/1422-0067/22/21/11548

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