Nervous System Injury and Neuroimaging of Zika Virus Infection
In 2016, World Health Organization announced Zika virus infection and its neurological sequalae are a public health emergency of global scope. Preliminary studies have confirmed a relationship between Zika virus infection and certain neurological disorders, including microcephaly and Guillain–Barre...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2018-04-01
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| Series: | Frontiers in Neurology |
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| Online Access: | http://journal.frontiersin.org/article/10.3389/fneur.2018.00227/full |
| _version_ | 1818142871357751296 |
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| author | Shanshan Wu Shanshan Wu Yu Zeng Alexander Lerner Bo Gao Meng Law |
| author_facet | Shanshan Wu Shanshan Wu Yu Zeng Alexander Lerner Bo Gao Meng Law |
| author_sort | Shanshan Wu |
| collection | DOAJ |
| description | In 2016, World Health Organization announced Zika virus infection and its neurological sequalae are a public health emergency of global scope. Preliminary studies have confirmed a relationship between Zika virus infection and certain neurological disorders, including microcephaly and Guillain–Barre syndrome (GBS). The neuroimaging features of microcephaly secondary to Zika virus infection include calcifications at the junction of gray–white matter and subcortical white matter with associated cortical abnormalities, diminution of white matter, large ventricles with or without hydrocephalus, cortical malformations, hypoplasia of cerebellum and brainstem, and enlargement of cerebellomedullary cistern. Contrast enhancement of the cauda equine nerve roots is the typical neuroimaging finding of GBS associated with Zika virus. This review describes the nervous system disorders and associated imaging findings seen in Zika virus infection, with the aim to improve the understanding of this disease. Imaging plays a key role on accurate diagnosis and prognostic evaluation of this disease. |
| first_indexed | 2024-12-11T11:22:39Z |
| format | Article |
| id | doaj.art-f71e9cb066ec45b8b218c605ec7c9524 |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-12-11T11:22:39Z |
| publishDate | 2018-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-f71e9cb066ec45b8b218c605ec7c95242022-12-22T01:09:08ZengFrontiers Media S.A.Frontiers in Neurology1664-22952018-04-01910.3389/fneur.2018.00227351021Nervous System Injury and Neuroimaging of Zika Virus InfectionShanshan Wu0Shanshan Wu1Yu Zeng2Alexander Lerner3Bo Gao4Meng Law5Department of Radiology, Affiliated Hospital of Guizhou Medical University, Guiyang, ChinaDepartment of Radiology, Yantai Yuhuangding Hospital, Yantai, ChinaDepartment of Radiology, Affiliated Hospital of Guizhou Medical University, Guiyang, ChinaDepartment of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, CA, United StatesDepartment of Radiology, Yantai Yuhuangding Hospital, Yantai, ChinaDepartment of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, CA, United StatesIn 2016, World Health Organization announced Zika virus infection and its neurological sequalae are a public health emergency of global scope. Preliminary studies have confirmed a relationship between Zika virus infection and certain neurological disorders, including microcephaly and Guillain–Barre syndrome (GBS). The neuroimaging features of microcephaly secondary to Zika virus infection include calcifications at the junction of gray–white matter and subcortical white matter with associated cortical abnormalities, diminution of white matter, large ventricles with or without hydrocephalus, cortical malformations, hypoplasia of cerebellum and brainstem, and enlargement of cerebellomedullary cistern. Contrast enhancement of the cauda equine nerve roots is the typical neuroimaging finding of GBS associated with Zika virus. This review describes the nervous system disorders and associated imaging findings seen in Zika virus infection, with the aim to improve the understanding of this disease. Imaging plays a key role on accurate diagnosis and prognostic evaluation of this disease.http://journal.frontiersin.org/article/10.3389/fneur.2018.00227/fullZika viruscentral nervous system infectionmicrocephalyGuillain-Barre syndromeneuroimaging |
| spellingShingle | Shanshan Wu Shanshan Wu Yu Zeng Alexander Lerner Bo Gao Meng Law Nervous System Injury and Neuroimaging of Zika Virus Infection Frontiers in Neurology Zika virus central nervous system infection microcephaly Guillain-Barre syndrome neuroimaging |
| title | Nervous System Injury and Neuroimaging of Zika Virus Infection |
| title_full | Nervous System Injury and Neuroimaging of Zika Virus Infection |
| title_fullStr | Nervous System Injury and Neuroimaging of Zika Virus Infection |
| title_full_unstemmed | Nervous System Injury and Neuroimaging of Zika Virus Infection |
| title_short | Nervous System Injury and Neuroimaging of Zika Virus Infection |
| title_sort | nervous system injury and neuroimaging of zika virus infection |
| topic | Zika virus central nervous system infection microcephaly Guillain-Barre syndrome neuroimaging |
| url | http://journal.frontiersin.org/article/10.3389/fneur.2018.00227/full |
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