Povidone-iodine for the management of oral mucositis during cancer therapy
Oral mucositis (OM) is a common and often dose-limiting side effect of cancer therapy. Povidone iodine (PVP-I) formulations have been shown to decrease the incidence and severity of OM, but the relevance of these findings remains unclear. The objective of the present study was to review evidence for...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2017-09-01
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| Series: | Oncology Reviews |
| Subjects: | |
| Online Access: | http://www.oncologyreviews.org/index.php/or/article/view/341 |
| _version_ | 1797963681638645760 |
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| author | Jeeve Kanagalingam Akhil Chopra Min Hee Hong Wisam Ibrahim Antonio Villalon Jin-Ching Lin |
| author_facet | Jeeve Kanagalingam Akhil Chopra Min Hee Hong Wisam Ibrahim Antonio Villalon Jin-Ching Lin |
| author_sort | Jeeve Kanagalingam |
| collection | DOAJ |
| description | Oral mucositis (OM) is a common and often dose-limiting side effect of cancer therapy. Povidone iodine (PVP-I) formulations have been shown to decrease the incidence and severity of OM, but the relevance of these findings remains unclear. The objective of the present study was to review evidence for the use of PVP-I for OM management. An algorithm identified relevant articles published online, and a panel of experts with experience in the management of OM reviewed the findings. Six studies fulfilled the criteria for full review. Two studies provided evidence of moderate quality. Two of the studies with negative findings were confounded by the use of PVP-I concentrations that are too low to be efficacious. The remaining two studies were found to have design flaws. There exists reasonable evidence to support a recommendation for the use of PVP-I in the management of cancer therapy-related OM. |
| first_indexed | 2024-04-11T01:32:05Z |
| format | Article |
| id | doaj.art-f71eadf748e0442d84d551c80da8dce1 |
| institution | Directory Open Access Journal |
| issn | 1970-5557 1970-5565 |
| language | English |
| last_indexed | 2024-04-11T01:32:05Z |
| publishDate | 2017-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Oncology Reviews |
| spelling | doaj.art-f71eadf748e0442d84d551c80da8dce12023-01-03T09:35:32ZengFrontiers Media S.A.Oncology Reviews1970-55571970-55652017-09-0111210.4081/oncol.2017.341233Povidone-iodine for the management of oral mucositis during cancer therapyJeeve Kanagalingam0Akhil Chopra1Min Hee Hong2Wisam Ibrahim3Antonio Villalon4Jin-Ching Lin5Lee Kong Chian School of Medicine, Johns Hopkins Singapore IMC and Tan Tock Seng Hospital, The ENT Clinic, Mount Elizabeth Novena Hospital, SingaporeOncoCare, Mount Elizabeth Medical Centre, Mount Elizabeth, SingaporeDivision of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Severance Hospital, Yonsei University Health System, SeoulIbn Nafees Medical Center, Abu DhabiManila Doctors Hospital, ManilaDepartment of Radiation Oncology, Taichung Veterans General Hospital, TaichungOral mucositis (OM) is a common and often dose-limiting side effect of cancer therapy. Povidone iodine (PVP-I) formulations have been shown to decrease the incidence and severity of OM, but the relevance of these findings remains unclear. The objective of the present study was to review evidence for the use of PVP-I for OM management. An algorithm identified relevant articles published online, and a panel of experts with experience in the management of OM reviewed the findings. Six studies fulfilled the criteria for full review. Two studies provided evidence of moderate quality. Two of the studies with negative findings were confounded by the use of PVP-I concentrations that are too low to be efficacious. The remaining two studies were found to have design flaws. There exists reasonable evidence to support a recommendation for the use of PVP-I in the management of cancer therapy-related OM.http://www.oncologyreviews.org/index.php/or/article/view/341Povidone iodinechemotherapyradiotherapycancermucositis. |
| spellingShingle | Jeeve Kanagalingam Akhil Chopra Min Hee Hong Wisam Ibrahim Antonio Villalon Jin-Ching Lin Povidone-iodine for the management of oral mucositis during cancer therapy Oncology Reviews Povidone iodine chemotherapy radiotherapy cancer mucositis. |
| title | Povidone-iodine for the management of oral mucositis during cancer therapy |
| title_full | Povidone-iodine for the management of oral mucositis during cancer therapy |
| title_fullStr | Povidone-iodine for the management of oral mucositis during cancer therapy |
| title_full_unstemmed | Povidone-iodine for the management of oral mucositis during cancer therapy |
| title_short | Povidone-iodine for the management of oral mucositis during cancer therapy |
| title_sort | povidone iodine for the management of oral mucositis during cancer therapy |
| topic | Povidone iodine chemotherapy radiotherapy cancer mucositis. |
| url | http://www.oncologyreviews.org/index.php/or/article/view/341 |
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