Interplay between Partial EMT and Cisplatin Resistance as the Drivers for Recurrence in HNSCC

Interplay between Partial EMT and Cisplatin Resistance as the Drivers for Recurrence in HNSCC

This study aims to investigate the role of partial epithelial to mesenchymal transition (pEMT)-related proteins in modulating Cisplatin resistance in head and neck squamous cell carcinoma (HNSCC). SCC-25 cells were pre-treated with TGF-beta1 followed by transient Krüppel-like Factor 4 (KLF4)-overexp...

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Bibliographic Details
Main Authors: Julia Ingruber, Jozsef Dudas, Susanne Sprung, Bianca Lungu, Felicitas Mungenast
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Biomedicines
Subjects:
partial EMT
cisplatin resistance
StrataQuest
SCC-25 cells
Online Access:https://www.mdpi.com/2227-9059/10/10/2482

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