What is new in the pathogenesis and management of erythema nodosum leprosum
Erythema nodosum leprosum (ENL) is a manifestation of type II lepra reaction, seen in lepromatous or borderline lepromatous leprosy. Although it is a common reaction encountered in clinical practice, there are an increasingly large number of newer updates in the pathophysiology and management of thi...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2020-01-01
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| Series: | Indian Dermatology Online Journal |
| Subjects: | |
| Online Access: | http://www.idoj.in/article.asp?issn=2229-5178;year=2020;volume=11;issue=4;spage=482;epage=492;aulast=Bhat |
| _version_ | 1818870762820337664 |
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| author | Ramesh M Bhat Tanvi P Vaidya |
| author_facet | Ramesh M Bhat Tanvi P Vaidya |
| author_sort | Ramesh M Bhat |
| collection | DOAJ |
| description | Erythema nodosum leprosum (ENL) is a manifestation of type II lepra reaction, seen in lepromatous or borderline lepromatous leprosy. Although it is a common reaction encountered in clinical practice, there are an increasingly large number of newer updates in the pathophysiology and management of this condition.The treatment options have expanded far beyond just thalidomide and steroids and now extends to TNF-α inhibitors, thalidomide analogs, tenidap, cyclosporine A, plasma exchange, and even IVIG amongst others. These updates and the current knowledge of ENL are summarized in this review. |
| first_indexed | 2024-12-19T12:12:11Z |
| format | Article |
| id | doaj.art-f721bb5606294345844b2c2d28287f37 |
| institution | Directory Open Access Journal |
| issn | 2229-5178 |
| language | English |
| last_indexed | 2024-12-19T12:12:11Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Dermatology Online Journal |
| spelling | doaj.art-f721bb5606294345844b2c2d28287f372022-12-21T20:22:10ZengWolters Kluwer Medknow PublicationsIndian Dermatology Online Journal2229-51782020-01-0111448249210.4103/idoj.IDOJ_561_19What is new in the pathogenesis and management of erythema nodosum leprosumRamesh M BhatTanvi P VaidyaErythema nodosum leprosum (ENL) is a manifestation of type II lepra reaction, seen in lepromatous or borderline lepromatous leprosy. Although it is a common reaction encountered in clinical practice, there are an increasingly large number of newer updates in the pathophysiology and management of this condition.The treatment options have expanded far beyond just thalidomide and steroids and now extends to TNF-α inhibitors, thalidomide analogs, tenidap, cyclosporine A, plasma exchange, and even IVIG amongst others. These updates and the current knowledge of ENL are summarized in this review.http://www.idoj.in/article.asp?issn=2229-5178;year=2020;volume=11;issue=4;spage=482;epage=492;aulast=Bhaterythema nodosum leprosumerythema nodosum leprosumlepra reactionthalidomide |
| spellingShingle | Ramesh M Bhat Tanvi P Vaidya What is new in the pathogenesis and management of erythema nodosum leprosum Indian Dermatology Online Journal erythema nodosum leprosum erythema nodosum leprosum lepra reaction thalidomide |
| title | What is new in the pathogenesis and management of erythema nodosum leprosum |
| title_full | What is new in the pathogenesis and management of erythema nodosum leprosum |
| title_fullStr | What is new in the pathogenesis and management of erythema nodosum leprosum |
| title_full_unstemmed | What is new in the pathogenesis and management of erythema nodosum leprosum |
| title_short | What is new in the pathogenesis and management of erythema nodosum leprosum |
| title_sort | what is new in the pathogenesis and management of erythema nodosum leprosum |
| topic | erythema nodosum leprosum erythema nodosum leprosum lepra reaction thalidomide |
| url | http://www.idoj.in/article.asp?issn=2229-5178;year=2020;volume=11;issue=4;spage=482;epage=492;aulast=Bhat |
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