Stratification and prognostic relevance of Jass’s molecular classification of colorectal cancer

Stratification and prognostic relevance of Jass’s molecular classification of colorectal cancer

Background: The current proposed model of colorectal tumorigenesis is based primarily on CpG island methylator phenotype (CIMP), microsatellite instability (MSI), KRAS, BRAF, and methylation status of 0-6-Methylguanine DNA Methyltransferase (MGMT) and classifies tumors into 5 subgroups. The aim of...

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Bibliographic Details
Main Authors: Inti eZlobec, Michel P Bihl, Anja eFoerster, Alex eRufle, Luigi eTerracciano, Alessandro eLugli
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-02-01
Series:Frontiers in Oncology
Subjects:
Methylation
colorectal cancer
prognosis
CpG Island Methylator Phenotype
Jass
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00007/full

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