Outcomes of neonatal hypothermia among very low birth weight infants: a Meta-analysis
Abstract Background Neonatal admission hypothermia (HT) is a frequently encountered problem in neonatal intensive care units (NICUs) and it has been linked to a higher risk of mortality and morbidity. However, there is a disparity in data in the existing literature regarding the prevalence and outco...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2021-09-01
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| Series: | Maternal Health, Neonatology and Perinatology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40748-021-00134-6 |
| _version_ | 1818915315877150720 |
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| author | Sagad Omer Obeid Mohamed Sara Mohamed Ibrahim Ahmed Reem Jamal Yousif Khidir Mutaz Tarig Hassan Ahmed Shaheen Mosab Hussen Mostafa Adam Basil Abubakr Yagoub Ibrahim Esra Osama Abdelrahman Elmahdi Abubaker Shadoul Mohamed Farah |
| author_facet | Sagad Omer Obeid Mohamed Sara Mohamed Ibrahim Ahmed Reem Jamal Yousif Khidir Mutaz Tarig Hassan Ahmed Shaheen Mosab Hussen Mostafa Adam Basil Abubakr Yagoub Ibrahim Esra Osama Abdelrahman Elmahdi Abubaker Shadoul Mohamed Farah |
| author_sort | Sagad Omer Obeid Mohamed |
| collection | DOAJ |
| description | Abstract Background Neonatal admission hypothermia (HT) is a frequently encountered problem in neonatal intensive care units (NICUs) and it has been linked to a higher risk of mortality and morbidity. However, there is a disparity in data in the existing literature regarding the prevalence and outcomes associated with HT in very low birth weight (VLBW) infants. This review aimed to provide further summary and analyses of the association between HT and adverse clinical outcomes in VLBW infants. Methods In July 2020, we conducted this review according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. A systematic database search was conducted in MEDLINE (PubMed), Google Scholar, ScienceDirect, World Health Organization Virtual Health Library, Cochrane Library databases, and System for Information on Grey Literature in Europe (SIGLE). We included studies that assessed the prevalence of HT and/or the association between HT and any adverse outcomes in VLBW infants. We calculated the pooled prevalence and Odds Ratio (OR) estimates with the corresponding 95% Confidence Interval (CI) using the Comprehensive meta-analysis software version 3.3 (Biostat, Engle-wood, NJ, USA; http://www.Meta-Analysis.com ). Results Eighteen studies that fulfilled the eligibility criteria were meta-analyzed. The pooled prevalence of HT among VLBW infants was 48.3% (95% CI, 42.0–54.7%). HT in VLBW infants was significantly associated with mortality (OR = 1.89; 1.72–2.09), intra-ventricular hemorrhage (OR = 1.86; 1.09–3.14), bronchopulmonary dysplasia (OR = 1.28; 1.16–1.40), neonatal sepsis (OR = 1.47; 1.09–2.49), and retinopathy of prematurity (OR = 1.45; 1.28–1.72). Conclusion Neonatal HT rate is high in VLBW infants and it is a risk factor for mortality and morbidity in VLBW infants. This review provides a comprehensive view of the prevalence and outcomes of HT in VLBW infants. |
| first_indexed | 2024-12-20T00:00:20Z |
| format | Article |
| id | doaj.art-f72271f3dc964b639735e211ed93a39f |
| institution | Directory Open Access Journal |
| issn | 2054-958X |
| language | English |
| last_indexed | 2024-12-20T00:00:20Z |
| publishDate | 2021-09-01 |
| publisher | BMC |
| record_format | Article |
| series | Maternal Health, Neonatology and Perinatology |
| spelling | doaj.art-f72271f3dc964b639735e211ed93a39f2022-12-21T20:00:52ZengBMCMaternal Health, Neonatology and Perinatology2054-958X2021-09-01711910.1186/s40748-021-00134-6Outcomes of neonatal hypothermia among very low birth weight infants: a Meta-analysisSagad Omer Obeid Mohamed0Sara Mohamed Ibrahim Ahmed1Reem Jamal Yousif Khidir2Mutaz Tarig Hassan Ahmed Shaheen3Mosab Hussen Mostafa Adam4Basil Abubakr Yagoub Ibrahim5Esra Osama Abdelrahman Elmahdi6Abubaker Shadoul Mohamed Farah7Faculty of Medicine, University of KhartoumFaculty of Medicine, University of KhartoumFaculty of Medicine, University of KhartoumFaculty of Medicine, University of KhartoumFaculty of Medicine, University of KhartoumFaculty of Medicine, University of KhartoumFaculty of Medicine, University of KhartoumFaculty of Medicine, University of KhartoumAbstract Background Neonatal admission hypothermia (HT) is a frequently encountered problem in neonatal intensive care units (NICUs) and it has been linked to a higher risk of mortality and morbidity. However, there is a disparity in data in the existing literature regarding the prevalence and outcomes associated with HT in very low birth weight (VLBW) infants. This review aimed to provide further summary and analyses of the association between HT and adverse clinical outcomes in VLBW infants. Methods In July 2020, we conducted this review according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. A systematic database search was conducted in MEDLINE (PubMed), Google Scholar, ScienceDirect, World Health Organization Virtual Health Library, Cochrane Library databases, and System for Information on Grey Literature in Europe (SIGLE). We included studies that assessed the prevalence of HT and/or the association between HT and any adverse outcomes in VLBW infants. We calculated the pooled prevalence and Odds Ratio (OR) estimates with the corresponding 95% Confidence Interval (CI) using the Comprehensive meta-analysis software version 3.3 (Biostat, Engle-wood, NJ, USA; http://www.Meta-Analysis.com ). Results Eighteen studies that fulfilled the eligibility criteria were meta-analyzed. The pooled prevalence of HT among VLBW infants was 48.3% (95% CI, 42.0–54.7%). HT in VLBW infants was significantly associated with mortality (OR = 1.89; 1.72–2.09), intra-ventricular hemorrhage (OR = 1.86; 1.09–3.14), bronchopulmonary dysplasia (OR = 1.28; 1.16–1.40), neonatal sepsis (OR = 1.47; 1.09–2.49), and retinopathy of prematurity (OR = 1.45; 1.28–1.72). Conclusion Neonatal HT rate is high in VLBW infants and it is a risk factor for mortality and morbidity in VLBW infants. This review provides a comprehensive view of the prevalence and outcomes of HT in VLBW infants.https://doi.org/10.1186/s40748-021-00134-6HypothermiaVery low birth weightMeta-analysis |
| spellingShingle | Sagad Omer Obeid Mohamed Sara Mohamed Ibrahim Ahmed Reem Jamal Yousif Khidir Mutaz Tarig Hassan Ahmed Shaheen Mosab Hussen Mostafa Adam Basil Abubakr Yagoub Ibrahim Esra Osama Abdelrahman Elmahdi Abubaker Shadoul Mohamed Farah Outcomes of neonatal hypothermia among very low birth weight infants: a Meta-analysis Maternal Health, Neonatology and Perinatology Hypothermia Very low birth weight Meta-analysis |
| title | Outcomes of neonatal hypothermia among very low birth weight infants: a Meta-analysis |
| title_full | Outcomes of neonatal hypothermia among very low birth weight infants: a Meta-analysis |
| title_fullStr | Outcomes of neonatal hypothermia among very low birth weight infants: a Meta-analysis |
| title_full_unstemmed | Outcomes of neonatal hypothermia among very low birth weight infants: a Meta-analysis |
| title_short | Outcomes of neonatal hypothermia among very low birth weight infants: a Meta-analysis |
| title_sort | outcomes of neonatal hypothermia among very low birth weight infants a meta analysis |
| topic | Hypothermia Very low birth weight Meta-analysis |
| url | https://doi.org/10.1186/s40748-021-00134-6 |
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