Anal intraepitelial neoplasia: a narrative review
Anal intraepitelial neoplasia (AIN) constitutes a major health problem in certain risk groups, such as patients with immunosuppression of varied origin, males who have sexual relations with other males, and females with a previous history of vaginal or cervical abnormalities in cytology. Its relatio...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Aran Ediciones
2016-01-01
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| Series: | Revista Espanola de Enfermedades Digestivas |
| Subjects: | |
| Online Access: | http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082016000100007&lng=en&tlng=en |
| _version_ | 1819026435953655808 |
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| author | Garazi Elorza Yolanda Saralegui José María Enríquez-Navascués Carlos Placer Leyre Velaz |
| author_facet | Garazi Elorza Yolanda Saralegui José María Enríquez-Navascués Carlos Placer Leyre Velaz |
| author_sort | Garazi Elorza |
| collection | DOAJ |
| description | Anal intraepitelial neoplasia (AIN) constitutes a major health problem in certain risk groups, such as patients with immunosuppression of varied origin, males who have sexual relations with other males, and females with a previous history of vaginal or cervical abnormalities in cytology. Its relationship with the human papillomavirus (HPV) infection has been well documented; however, many of the factors involved in the progression and regression of the viral infection to dysplasia and anal carcinoma are unknown. AIN can be diagnosed through cytology of the anal canal or biopsy guided by high-resolution anoscopy. However, the need for these techniques in high-risk groups remains controversial. Treatment depends on the risk factors and given the high morbidity and high recurrence rates the utility of the different local treatments is still a subject of debate. Surgical biopsy is justified only in the case of progression suggesting lesions. The role of the vaccination in high-risk patients as primary prevention has been debated by different groups. However, there is no general consensus on its use or on the need for screening this population. |
| first_indexed | 2024-12-21T05:26:32Z |
| format | Article |
| id | doaj.art-f725dcce6909429eb80e105cb4ff9cee |
| institution | Directory Open Access Journal |
| issn | 1130-0108 |
| language | English |
| last_indexed | 2024-12-21T05:26:32Z |
| publishDate | 2016-01-01 |
| publisher | Aran Ediciones |
| record_format | Article |
| series | Revista Espanola de Enfermedades Digestivas |
| spelling | doaj.art-f725dcce6909429eb80e105cb4ff9cee2022-12-21T19:14:41ZengAran EdicionesRevista Espanola de Enfermedades Digestivas1130-01082016-01-0110813139S1130-01082016000100007Anal intraepitelial neoplasia: a narrative reviewGarazi Elorza0Yolanda Saralegui1José María Enríquez-Navascués2Carlos Placer3Leyre Velaz4Hospital Universitario DonostiaHospital Universitario DonostiaHospital Universitario DonostiaHospital Universitario DonostiaHospital Universitario DonostiaAnal intraepitelial neoplasia (AIN) constitutes a major health problem in certain risk groups, such as patients with immunosuppression of varied origin, males who have sexual relations with other males, and females with a previous history of vaginal or cervical abnormalities in cytology. Its relationship with the human papillomavirus (HPV) infection has been well documented; however, many of the factors involved in the progression and regression of the viral infection to dysplasia and anal carcinoma are unknown. AIN can be diagnosed through cytology of the anal canal or biopsy guided by high-resolution anoscopy. However, the need for these techniques in high-risk groups remains controversial. Treatment depends on the risk factors and given the high morbidity and high recurrence rates the utility of the different local treatments is still a subject of debate. Surgical biopsy is justified only in the case of progression suggesting lesions. The role of the vaccination in high-risk patients as primary prevention has been debated by different groups. However, there is no general consensus on its use or on the need for screening this population.http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082016000100007&lng=en&tlng=enNeoplasia intraepitelial analAnuscopia de alta resoluciónCarcinoma analVacuna del virus del papiloma humano |
| spellingShingle | Garazi Elorza Yolanda Saralegui José María Enríquez-Navascués Carlos Placer Leyre Velaz Anal intraepitelial neoplasia: a narrative review Revista Espanola de Enfermedades Digestivas Neoplasia intraepitelial anal Anuscopia de alta resolución Carcinoma anal Vacuna del virus del papiloma humano |
| title | Anal intraepitelial neoplasia: a narrative review |
| title_full | Anal intraepitelial neoplasia: a narrative review |
| title_fullStr | Anal intraepitelial neoplasia: a narrative review |
| title_full_unstemmed | Anal intraepitelial neoplasia: a narrative review |
| title_short | Anal intraepitelial neoplasia: a narrative review |
| title_sort | anal intraepitelial neoplasia a narrative review |
| topic | Neoplasia intraepitelial anal Anuscopia de alta resolución Carcinoma anal Vacuna del virus del papiloma humano |
| url | http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082016000100007&lng=en&tlng=en |
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