Use of Ferulic Acid in the Management of Diabetes Mellitus and Its Complications
Diabetes mellitus, a metabolic disease mainly characterized by hyperglycemia, is becoming a serious social health problem worldwide with growing prevalence. Many natural compounds have been found to be effective in the prevention and treatment of diabetes, with negligible toxic effects. Ferulic acid...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-09-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/27/18/6010 |
| _version_ | 1797484305585274880 |
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| author | Xu Li Jingxian Wu Fanxing Xu Chun Chu Xiang Li Xinyi Shi Wen Zheng Zhenzhong Wang Ying Jia Wei Xiao |
| author_facet | Xu Li Jingxian Wu Fanxing Xu Chun Chu Xiang Li Xinyi Shi Wen Zheng Zhenzhong Wang Ying Jia Wei Xiao |
| author_sort | Xu Li |
| collection | DOAJ |
| description | Diabetes mellitus, a metabolic disease mainly characterized by hyperglycemia, is becoming a serious social health problem worldwide with growing prevalence. Many natural compounds have been found to be effective in the prevention and treatment of diabetes, with negligible toxic effects. Ferulic acid (FA), a phenolic compound commonly found in medicinal herbs and the daily diet, was proved to have several pharmacological effects such as antihyperglycemic, antihyperlipidemic and antioxidant actions, which are beneficial to the management of diabetes and its complications. Data from PubMed, EM-BASE, Web of Science and CNKI were searched with the keywords ferulic acid and diabetes mellitus. Finally, 28 articles were identified after literature screening, and the research progress of FA for the management of DM and its complications was summarized in the review, in order to provide references for further research and medical applications of FA. |
| first_indexed | 2024-03-09T23:01:35Z |
| format | Article |
| id | doaj.art-f726eec888634213a2ecf1366e444f5f |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-09T23:01:35Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-f726eec888634213a2ecf1366e444f5f2023-11-23T18:02:44ZengMDPI AGMolecules1420-30492022-09-012718601010.3390/molecules27186010Use of Ferulic Acid in the Management of Diabetes Mellitus and Its ComplicationsXu Li0Jingxian Wu1Fanxing Xu2Chun Chu3Xiang Li4Xinyi Shi5Wen Zheng6Zhenzhong Wang7Ying Jia8Wei Xiao9Jiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang 222001, ChinaWuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, ChinaJiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang 222001, ChinaSchool of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, ChinaSchool of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, ChinaWuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, ChinaWuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, ChinaJiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang 222001, ChinaFaculty of Functional Food and Wine, Shenyang Pharmaceutical University, Shenyang 110016, ChinaJiangsu Kanion Pharmaceutical Co., Ltd., Lianyungang 222001, ChinaDiabetes mellitus, a metabolic disease mainly characterized by hyperglycemia, is becoming a serious social health problem worldwide with growing prevalence. Many natural compounds have been found to be effective in the prevention and treatment of diabetes, with negligible toxic effects. Ferulic acid (FA), a phenolic compound commonly found in medicinal herbs and the daily diet, was proved to have several pharmacological effects such as antihyperglycemic, antihyperlipidemic and antioxidant actions, which are beneficial to the management of diabetes and its complications. Data from PubMed, EM-BASE, Web of Science and CNKI were searched with the keywords ferulic acid and diabetes mellitus. Finally, 28 articles were identified after literature screening, and the research progress of FA for the management of DM and its complications was summarized in the review, in order to provide references for further research and medical applications of FA.https://www.mdpi.com/1420-3049/27/18/6010ferulic aciddiabetes mellitusdiabetic complications |
| spellingShingle | Xu Li Jingxian Wu Fanxing Xu Chun Chu Xiang Li Xinyi Shi Wen Zheng Zhenzhong Wang Ying Jia Wei Xiao Use of Ferulic Acid in the Management of Diabetes Mellitus and Its Complications Molecules ferulic acid diabetes mellitus diabetic complications |
| title | Use of Ferulic Acid in the Management of Diabetes Mellitus and Its Complications |
| title_full | Use of Ferulic Acid in the Management of Diabetes Mellitus and Its Complications |
| title_fullStr | Use of Ferulic Acid in the Management of Diabetes Mellitus and Its Complications |
| title_full_unstemmed | Use of Ferulic Acid in the Management of Diabetes Mellitus and Its Complications |
| title_short | Use of Ferulic Acid in the Management of Diabetes Mellitus and Its Complications |
| title_sort | use of ferulic acid in the management of diabetes mellitus and its complications |
| topic | ferulic acid diabetes mellitus diabetic complications |
| url | https://www.mdpi.com/1420-3049/27/18/6010 |
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