Mechanism of agonist-induced activation of the human itch receptor MRGPRX1

Mechanism of agonist-induced activation of the human itch receptor MRGPRX1

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Mas-related G-protein-coupled receptors X1-X4 (MRGPRX1-X4) are 4 primate-specific receptors that are recently reported to be responsible for many biological processes, including itch sensation, pain transmission, and inflammatory reactions. MRGPRX1 is the first identified human MRGPR, and its expres...

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Bibliographic Details
Main Authors: Bing Gan, Leiye Yu, Haifeng Yang, Haizhan Jiao, Bin Pang, Yian Chen, Chen Wang, Rui Lv, Hongli Hu, Zhijian Cao, Ruobing Ren
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-06-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286997/?tool=EBI

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