An Inchworm and Stick-Slip Dual Mode Piezoelectric Linear Actuator for Cell Injection
Cell injection system for biomedical engineering demands that actuators have large stroke, high resolution and speed for cell positioning and injection. Single mode piezoelectric actuators could meet some of these requirements but hardly all. Stick-slip actuator is easy to achieve high-speed operati...
| Main Authors: | , , , , , , |
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| Format: | Article |
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IEEE
2023-01-01
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| Series: | IEEE Access |
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| Online Access: | https://ieeexplore.ieee.org/document/10148984/ |
| _version_ | 1797772627804160000 |
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| author | Jijie Ma Junhao Li Xiaohui Lin Xinsheng He Yili Hu Jianping Li Jianming Wen |
| author_facet | Jijie Ma Junhao Li Xiaohui Lin Xinsheng He Yili Hu Jianping Li Jianming Wen |
| author_sort | Jijie Ma |
| collection | DOAJ |
| description | Cell injection system for biomedical engineering demands that actuators have large stroke, high resolution and speed for cell positioning and injection. Single mode piezoelectric actuators could meet some of these requirements but hardly all. Stick-slip actuator is easy to achieve high-speed operation, but it is prone to setback; The speed characteristics of the inchworm actuator are lower than those of the stick-slip actuator, but the step is more stable and the setback is lower. This study proposes an inchworm and stick-slip dual mode piezoelectric actuator (ISSPA) for cell injection. It integrates two working modes into one actuator and both modes drive the same slider. The stick-slip mode works at high frequency for fast positioning to the cell and the inchworm mode drives the needle to puncture the cell membrane and accurately locates to the specified location. The structure and working principle of the ISSPA are provided. A prototype of the proposed ISSPA is fabricated and experiments are conducted. When the driving voltage of the piezoelectric stack is 100 V and the frequency is 500 Hz,the maximum speed of the ISSPA is 2.287 mm/s in the stick-slip mode. When the driving voltage of the piezoelectric stack is 60 V, the frequency is 3 Hz and the load is 0.5 kg,the minimum step displacement is 57 nm in inchworm mode. Demonstration of cell injection is carried out by using the ISSPA to positioning and puncturing a zebrafish embryo. Fast positioning with the stick-slip mode and accurate puncture with the inchworm mode are achieved with the ISSPA alone, taking 12 seconds for the whole injection process. It could be expected to apply the ISSPA to cells with wide range of diameter, as the frequency of the stick-slick mode and the voltage of the inchworm mode could be well regulated. |
| first_indexed | 2024-03-12T21:53:42Z |
| format | Article |
| id | doaj.art-f72d095caf6f40a2bd5e3c8fce280604 |
| institution | Directory Open Access Journal |
| issn | 2169-3536 |
| language | English |
| last_indexed | 2024-03-12T21:53:42Z |
| publishDate | 2023-01-01 |
| publisher | IEEE |
| record_format | Article |
| series | IEEE Access |
| spelling | doaj.art-f72d095caf6f40a2bd5e3c8fce2806042023-07-25T23:00:58ZengIEEEIEEE Access2169-35362023-01-0111705347054110.1109/ACCESS.2023.328527110148984An Inchworm and Stick-Slip Dual Mode Piezoelectric Linear Actuator for Cell InjectionJijie Ma0https://orcid.org/0000-0001-7389-8219Junhao Li1Xiaohui Lin2Xinsheng He3Yili Hu4https://orcid.org/0000-0003-1074-8779Jianping Li5https://orcid.org/0000-0002-1943-0372Jianming Wen6https://orcid.org/0000-0002-4630-0194Zhejiang Province Key Laboratory of Urban Rail Transit Intelligent Operation and Maintenance Technology and Equipment, Zhejiang Normal University, Jinhua, ChinaCollege of Physics and Electronic Information Engineering, Zhejiang Normal University, Jinhua, ChinaInstitute of Precision Machinery and Smart Structure, College of Engineering, Zhejiang Normal University, Jinhua, ChinaZhejiang Province Key Laboratory of Urban Rail Transit Intelligent Operation and Maintenance Technology and Equipment, Zhejiang Normal University, Jinhua, ChinaZhejiang Province Key Laboratory of Urban Rail Transit Intelligent Operation and Maintenance Technology and Equipment, Zhejiang Normal University, Jinhua, ChinaZhejiang Province Key Laboratory of Urban Rail Transit Intelligent Operation and Maintenance Technology and Equipment, Zhejiang Normal University, Jinhua, ChinaZhejiang Province Key Laboratory of Urban Rail Transit Intelligent Operation and Maintenance Technology and Equipment, Zhejiang Normal University, Jinhua, ChinaCell injection system for biomedical engineering demands that actuators have large stroke, high resolution and speed for cell positioning and injection. Single mode piezoelectric actuators could meet some of these requirements but hardly all. Stick-slip actuator is easy to achieve high-speed operation, but it is prone to setback; The speed characteristics of the inchworm actuator are lower than those of the stick-slip actuator, but the step is more stable and the setback is lower. This study proposes an inchworm and stick-slip dual mode piezoelectric actuator (ISSPA) for cell injection. It integrates two working modes into one actuator and both modes drive the same slider. The stick-slip mode works at high frequency for fast positioning to the cell and the inchworm mode drives the needle to puncture the cell membrane and accurately locates to the specified location. The structure and working principle of the ISSPA are provided. A prototype of the proposed ISSPA is fabricated and experiments are conducted. When the driving voltage of the piezoelectric stack is 100 V and the frequency is 500 Hz,the maximum speed of the ISSPA is 2.287 mm/s in the stick-slip mode. When the driving voltage of the piezoelectric stack is 60 V, the frequency is 3 Hz and the load is 0.5 kg,the minimum step displacement is 57 nm in inchworm mode. Demonstration of cell injection is carried out by using the ISSPA to positioning and puncturing a zebrafish embryo. Fast positioning with the stick-slip mode and accurate puncture with the inchworm mode are achieved with the ISSPA alone, taking 12 seconds for the whole injection process. It could be expected to apply the ISSPA to cells with wide range of diameter, as the frequency of the stick-slick mode and the voltage of the inchworm mode could be well regulated.https://ieeexplore.ieee.org/document/10148984/Piezoelectric actuatorcell injectiondual mode |
| spellingShingle | Jijie Ma Junhao Li Xiaohui Lin Xinsheng He Yili Hu Jianping Li Jianming Wen An Inchworm and Stick-Slip Dual Mode Piezoelectric Linear Actuator for Cell Injection IEEE Access Piezoelectric actuator cell injection dual mode |
| title | An Inchworm and Stick-Slip Dual Mode Piezoelectric Linear Actuator for Cell Injection |
| title_full | An Inchworm and Stick-Slip Dual Mode Piezoelectric Linear Actuator for Cell Injection |
| title_fullStr | An Inchworm and Stick-Slip Dual Mode Piezoelectric Linear Actuator for Cell Injection |
| title_full_unstemmed | An Inchworm and Stick-Slip Dual Mode Piezoelectric Linear Actuator for Cell Injection |
| title_short | An Inchworm and Stick-Slip Dual Mode Piezoelectric Linear Actuator for Cell Injection |
| title_sort | inchworm and stick slip dual mode piezoelectric linear actuator for cell injection |
| topic | Piezoelectric actuator cell injection dual mode |
| url | https://ieeexplore.ieee.org/document/10148984/ |
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