Factors associated with oxygen requirement and persistent symptoms 1 year after severe COVID-19 infection
Objective We aimed to describe the prevalence and factors associated with the need for supplemental oxygen and persistent symptoms 1 year after severe SARS-CoV-2 infection. Methods In this historical cohort and nested case–control study, we included adults with severe COVID-19 (requiring admission t...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2023-05-01
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| Series: | Journal of International Medical Research |
| Online Access: | https://doi.org/10.1177/03000605231173317 |
| _version_ | 1797828702309974016 |
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| author | María Natalia Serrano Oscar Mauricio Muñoz Camilo Rueda Alejandra Cañas- Arboleda Juan David Botero Marlon Mauricio Bustos |
| author_facet | María Natalia Serrano Oscar Mauricio Muñoz Camilo Rueda Alejandra Cañas- Arboleda Juan David Botero Marlon Mauricio Bustos |
| author_sort | María Natalia Serrano |
| collection | DOAJ |
| description | Objective We aimed to describe the prevalence and factors associated with the need for supplemental oxygen and persistent symptoms 1 year after severe SARS-CoV-2 infection. Methods In this historical cohort and nested case–control study, we included adults with severe COVID-19 (requiring admission to the intensive care unit or invasive mechanical ventilation). We evaluated factors associated with a need for supplemental oxygen and persistent symptoms 1 year after severe infection. Results We included 135 patients (median age 62 years, 30% women). At 1-year follow-up, the main symptoms were dyspnea (32%), myalgia (9%), cough (7%), anxiety (4%), and depression (5%); 12.59% of patients had prolonged requirement for supplemental oxygen. Factors associated with a persistent requirement for supplemental oxygen were female sex (odds ratio 3.15, 95% confidence interval 1.11–8.90) and Charlson Comorbidity Index > 4 (odds ratio 1.60, 95% confidence interval 1.20–2.12). Conclusions We found that a high prevalence of supplemental oxygen requirement 1 year after severe COVID infection was associated with female sex and a baseline high rate of comorbidities. It is unknown whether this prevalence was related to other factors, such as the altitude at which patients lived. More than half of patients had prolonged post-COVID syndrome. |
| first_indexed | 2024-04-09T13:09:43Z |
| format | Article |
| id | doaj.art-f72fb0a940e8498196b910afa174f08b |
| institution | Directory Open Access Journal |
| issn | 1473-2300 |
| language | English |
| last_indexed | 2024-04-09T13:09:43Z |
| publishDate | 2023-05-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of International Medical Research |
| spelling | doaj.art-f72fb0a940e8498196b910afa174f08b2023-05-12T10:03:48ZengSAGE PublishingJournal of International Medical Research1473-23002023-05-015110.1177/03000605231173317Factors associated with oxygen requirement and persistent symptoms 1 year after severe COVID-19 infectionMaría Natalia SerranoOscar Mauricio MuñozCamilo RuedaAlejandra Cañas- ArboledaJuan David BoteroMarlon Mauricio BustosObjective We aimed to describe the prevalence and factors associated with the need for supplemental oxygen and persistent symptoms 1 year after severe SARS-CoV-2 infection. Methods In this historical cohort and nested case–control study, we included adults with severe COVID-19 (requiring admission to the intensive care unit or invasive mechanical ventilation). We evaluated factors associated with a need for supplemental oxygen and persistent symptoms 1 year after severe infection. Results We included 135 patients (median age 62 years, 30% women). At 1-year follow-up, the main symptoms were dyspnea (32%), myalgia (9%), cough (7%), anxiety (4%), and depression (5%); 12.59% of patients had prolonged requirement for supplemental oxygen. Factors associated with a persistent requirement for supplemental oxygen were female sex (odds ratio 3.15, 95% confidence interval 1.11–8.90) and Charlson Comorbidity Index > 4 (odds ratio 1.60, 95% confidence interval 1.20–2.12). Conclusions We found that a high prevalence of supplemental oxygen requirement 1 year after severe COVID infection was associated with female sex and a baseline high rate of comorbidities. It is unknown whether this prevalence was related to other factors, such as the altitude at which patients lived. More than half of patients had prolonged post-COVID syndrome.https://doi.org/10.1177/03000605231173317 |
| spellingShingle | María Natalia Serrano Oscar Mauricio Muñoz Camilo Rueda Alejandra Cañas- Arboleda Juan David Botero Marlon Mauricio Bustos Factors associated with oxygen requirement and persistent symptoms 1 year after severe COVID-19 infection Journal of International Medical Research |
| title | Factors associated with oxygen requirement and persistent symptoms 1 year after severe COVID-19 infection |
| title_full | Factors associated with oxygen requirement and persistent symptoms 1 year after severe COVID-19 infection |
| title_fullStr | Factors associated with oxygen requirement and persistent symptoms 1 year after severe COVID-19 infection |
| title_full_unstemmed | Factors associated with oxygen requirement and persistent symptoms 1 year after severe COVID-19 infection |
| title_short | Factors associated with oxygen requirement and persistent symptoms 1 year after severe COVID-19 infection |
| title_sort | factors associated with oxygen requirement and persistent symptoms 1 year after severe covid 19 infection |
| url | https://doi.org/10.1177/03000605231173317 |
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