| Summary: | Introduction: "premature rupture of membranes" (PROM) refers to the chorioamnionitis membranes
spontaneously rupturing before the start of labour. This study compares the safety and effectiveness of
intracervical dinoprostone gel and sublingual misoprostol for cervical ripening in term PROM. Methods:
This is an analytical cross-sectional study including 100 term mothers with spontaneous PROM
attending obstetric casualty at the Department of Obstetrics and Gynaecology, Government Raja
Mirasudhar Hospital, Thanjavur, India, selected using a multistage sampling technique from the study
period of February 2021 – November 2021 (10 months). One hundred samples were assigned randomly
into two groups which were 50 in each group as group A (Misoprostol group) and group B (Dinoprostone
gel group). Results: In group A, the study participants' median ages were 25 years (8.48) and 26.2
years (6.42), respectively. The difference in age averages between groups A and B was found to be
6.03, with a statistically significant p-value of 0.016. In both groups, the induction delivery interval was
nearly equal. The link between the Indication for Lower Segmental Caesarean Section and both groups
was statistically significant. When the two groups' delivery modes were compared, natural labour was
shown to be statistically significant (p = 0.048). Normal and abnormal heart rates were statistically
significant for the association between fetal heart rate and the groups, respectively, with chi-square
values of 6.854 and 9.281 (p = 0.022 and 0.013, respectively). The remaining groups were not
statistically significant. Conclusion: It was concluded that though sublingual misoprostol is more
efficacious than intracervical dinoprostone, its safety margin is significantly less; hence, misoprostol
induction should be done only in a double setup under medical supervision.
|
|---|