Inferring the physical properties of yeast chromatin through Bayesian analysis of whole nucleus simulations

Inferring the physical properties of yeast chromatin through Bayesian analysis of whole nucleus simulations

Abstract Background The structure and mechanical properties of chromatin impact DNA functions and nuclear architecture but remain poorly understood. In budding yeast, a simple polymer model with minimal sequence-specific constraints and a small number of structural parameters can explain diverse exp...

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Bibliographic Details
Main Authors: Jean-Michel Arbona, Sébastien Herbert, Emmanuelle Fabre, Christophe Zimmer
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Genome Biology
Subjects:
Chromatin
Chromosomes
Nuclear architecture
Polymer models
Yeast
Online Access:http://link.springer.com/article/10.1186/s13059-017-1199-x

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