Is the Way to Fight Cancer Paved with Gold? Metal-Based Carbene Complexes with Multiple and Fascinating Biological Features

Is the Way to Fight Cancer Paved with Gold? Metal-Based Carbene Complexes with Multiple and Fascinating Biological Features

Herein, we report the synthesis and the multiple anti-tumor properties of new gold and silver carbene complexes. The chemical modifications, grounded on our previous studies, led us to identify a good lead complex, gold-based, whose biological features are very exciting and promising in the anti-can...

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Bibliographic Details
Main Authors: Domenico Iacopetta, Camillo Rosano, Marco Sirignano, Annaluisa Mariconda, Jessica Ceramella, Marco Ponassi, Carmela Saturnino, Maria Stefania Sinicropi, Pasquale Longo
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Pharmaceuticals
Subjects:
human topoisomerases I and II
tubulin
women cancers
docking studies
carbene complexes
Online Access:https://www.mdpi.com/1424-8247/13/5/91

Internet

https://www.mdpi.com/1424-8247/13/5/91

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