| Summary: | Background: Psoriasis is a chronic inflammatory papulosquamous disorder. Psoriasiform dermatitis on the other hand is a frequently encountered terminology in a variety of inflammatory dermatoses. It poses diagnostic challenge and may require a histopathological confirmation for the diagnosis. Aim and Objectives: To evaluate and correlate clinical and histomorphological features in psoriasis and Psoriasiform dermatitis. Material and Methods: This was an observational study involving 100 patients, with a clinical diagnosis of psoriasis or Psoriasiform dermatitis as one of the differential diagnoses and its correlation with histopathological features along with CD34 immunostaining differences. Results: In our study, there was significant clinical and histopathological concordance in psoriasis and Psoriasiform dermatitis. Fifty cases each of Psoriasiform dermatitis and psoriasis were enrolled of which middle age group was affected more with slight male preponderance. The histological variation between psoriasis and Psoriasiform dermatitis was determined and CD34 immunohistochemical marker was applied to further aid the diagnosis. Conclusion: The present study emphasizes clinical and histopathological concordance of cases of psoriasis and Psoriasiform dermatitis due to significant difference in patient management and need for further work up.
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