MRI IN THE ASSESSMENT OF TUMOR RESPONSE TO CHEMORADIOTHERAPY IN PATIENTS WITH LOCALLY ADVANCED CERVICAL CANCER
Objective: to evaluate the ability of high-field MRI to assess tumor response to chemoradiotherapy in patients with locally advanced cervical cancer. Material and methods. The study involved 43 patients. MRI was performed using a 1.5 Tesla MAGNETOM ESSENZA scanner (SIEMENS, Germany) with a magnetic...
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Format: | Article |
Language: | Russian |
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Russian Academy of Sciences, Tomsk National Research Medical Center
2016-02-01
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Series: | Сибирский онкологический журнал |
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Online Access: | https://www.siboncoj.ru/jour/article/view/174 |
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author | N. G. Trukhacheva I. G. Frolova L. A. Kolomiets A. V. Usova E. G. Grigorjev S. A. Velichko O. N. Churuksaeva O. V. Shpileva |
author_facet | N. G. Trukhacheva I. G. Frolova L. A. Kolomiets A. V. Usova E. G. Grigorjev S. A. Velichko O. N. Churuksaeva O. V. Shpileva |
author_sort | N. G. Trukhacheva |
collection | DOAJ |
description | Objective: to evaluate the ability of high-field MRI to assess tumor response to chemoradiotherapy in patients with locally advanced cervical cancer. Material and methods. The study involved 43 patients. MRI was performed using a 1.5 Tesla MAGNETOM ESSENZA scanner (SIEMENS, Germany) with a magnetic field strength of 1.5 T. Intravenous bolus injection of paramagnetic contrast agent was used to assess the tumor spread and determine the tumor boundaries and its structure. Dynamic series of sections and delayed scans in standard T1-weighted sequence were obtained. Results. Dynamic contrast-enhanced MRI was shown to be a highly informative method that can be used to monitor the process of combined chemotherapy and radiation therapy in the treatment of patients with cervical cancer. It permits the objective assessment of the dynamics of tumor regression, changes in tumor vascularity and regional lymph node status. |
first_indexed | 2024-04-10T01:54:55Z |
format | Article |
id | doaj.art-f7383242c8264ce788afb6b2f6887e9f |
institution | Directory Open Access Journal |
issn | 1814-4861 2312-3168 |
language | Russian |
last_indexed | 2025-03-14T10:10:20Z |
publishDate | 2016-02-01 |
publisher | Russian Academy of Sciences, Tomsk National Research Medical Center |
record_format | Article |
series | Сибирский онкологический журнал |
spelling | doaj.art-f7383242c8264ce788afb6b2f6887e9f2025-03-02T11:16:05ZrusRussian Academy of Sciences, Tomsk National Research Medical CenterСибирский онкологический журнал1814-48612312-31682016-02-01158491174MRI IN THE ASSESSMENT OF TUMOR RESPONSE TO CHEMORADIOTHERAPY IN PATIENTS WITH LOCALLY ADVANCED CERVICAL CANCERN. G. Trukhacheva0I. G. Frolova1L. A. Kolomiets2A. V. Usova3E. G. Grigorjev4S. A. Velichko5O. N. Churuksaeva6O. V. Shpileva7Tomsk Cancer Research InstituteTomsk Cancer Research InstituteTomsk Cancer Research Institute; Siberian State Medical University, TomskTomsk Cancer Research InstituteTomsk Cancer Research InstituteTomsk Cancer Research InstituteTomsk Cancer Research InstituteTomsk Cancer Research InstituteObjective: to evaluate the ability of high-field MRI to assess tumor response to chemoradiotherapy in patients with locally advanced cervical cancer. Material and methods. The study involved 43 patients. MRI was performed using a 1.5 Tesla MAGNETOM ESSENZA scanner (SIEMENS, Germany) with a magnetic field strength of 1.5 T. Intravenous bolus injection of paramagnetic contrast agent was used to assess the tumor spread and determine the tumor boundaries and its structure. Dynamic series of sections and delayed scans in standard T1-weighted sequence were obtained. Results. Dynamic contrast-enhanced MRI was shown to be a highly informative method that can be used to monitor the process of combined chemotherapy and radiation therapy in the treatment of patients with cervical cancer. It permits the objective assessment of the dynamics of tumor regression, changes in tumor vascularity and regional lymph node status.https://www.siboncoj.ru/jour/article/view/174resonance imaging, cervical cancer, response to chemoradiotherapy |
spellingShingle | N. G. Trukhacheva I. G. Frolova L. A. Kolomiets A. V. Usova E. G. Grigorjev S. A. Velichko O. N. Churuksaeva O. V. Shpileva MRI IN THE ASSESSMENT OF TUMOR RESPONSE TO CHEMORADIOTHERAPY IN PATIENTS WITH LOCALLY ADVANCED CERVICAL CANCER Сибирский онкологический журнал resonance imaging, cervical cancer, response to chemoradiotherapy |
title | MRI IN THE ASSESSMENT OF TUMOR RESPONSE TO CHEMORADIOTHERAPY IN PATIENTS WITH LOCALLY ADVANCED CERVICAL CANCER |
title_full | MRI IN THE ASSESSMENT OF TUMOR RESPONSE TO CHEMORADIOTHERAPY IN PATIENTS WITH LOCALLY ADVANCED CERVICAL CANCER |
title_fullStr | MRI IN THE ASSESSMENT OF TUMOR RESPONSE TO CHEMORADIOTHERAPY IN PATIENTS WITH LOCALLY ADVANCED CERVICAL CANCER |
title_full_unstemmed | MRI IN THE ASSESSMENT OF TUMOR RESPONSE TO CHEMORADIOTHERAPY IN PATIENTS WITH LOCALLY ADVANCED CERVICAL CANCER |
title_short | MRI IN THE ASSESSMENT OF TUMOR RESPONSE TO CHEMORADIOTHERAPY IN PATIENTS WITH LOCALLY ADVANCED CERVICAL CANCER |
title_sort | mri in the assessment of tumor response to chemoradiotherapy in patients with locally advanced cervical cancer |
topic | resonance imaging, cervical cancer, response to chemoradiotherapy |
url | https://www.siboncoj.ru/jour/article/view/174 |
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