Optimizing the Maximum Recovery of Dihydromyricetin from Chinese Vine Tea, Ampelopsis grossedentata, Using Response Surface Methodology
This work provides an optimized extraction approach intended to maximize the recovery of dihydromyricetin (DHM) from Chinese vine tea (Ampelopsis grossedentata) leaves. The presented work adopts a Box-Behnken design as a response surface methodology to understand the role and influence of specific e...
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| Format: | Article |
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MDPI AG
2017-12-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/22/12/2250 |
| _version_ | 1818235893409906688 |
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| author | Umair Muhammad Hedong Lu Juan Wang Jinzhi Han Xiaoyu Zhu Zhaoxin Lu Sultana Tayyaba Yousef I. Hassan |
| author_facet | Umair Muhammad Hedong Lu Juan Wang Jinzhi Han Xiaoyu Zhu Zhaoxin Lu Sultana Tayyaba Yousef I. Hassan |
| author_sort | Umair Muhammad |
| collection | DOAJ |
| description | This work provides an optimized extraction approach intended to maximize the recovery of dihydromyricetin (DHM) from Chinese vine tea (Ampelopsis grossedentata) leaves. The presented work adopts a Box-Behnken design as a response surface methodology to understand the role and influence of specific extraction parameters including: time, temperature, and solvent composition/ethanol (%) on DHM final yields. Initially, single factor experiments were used to delineate the role of above factors (temperature, time, and solvent composition) before proceeding with three factors-three levels Box-Behnken design with 17 separate runs to assess the effect of multifactorial treatments on DHM recovery rates. The collected data shows that independent variables (solvent composition, time, and temperature) can significantly affect DHM recovery rates with maximum yields resulting from a combined 60 °C, 60% aqueous ethanol, and 180 min treatment. From the empirical point of view, the above optimized extraction protocol can substantially enhance processing and profitability margins with a minimum need of interventions or associated costs. |
| first_indexed | 2024-12-12T12:01:12Z |
| format | Article |
| id | doaj.art-f73a7fdafc1d4c12b3aa8116394e9918 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-12T12:01:12Z |
| publishDate | 2017-12-01 |
| publisher | MDPI AG |
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| series | Molecules |
| spelling | doaj.art-f73a7fdafc1d4c12b3aa8116394e99182022-12-22T00:25:06ZengMDPI AGMolecules1420-30492017-12-012212225010.3390/molecules22122250molecules22122250Optimizing the Maximum Recovery of Dihydromyricetin from Chinese Vine Tea, Ampelopsis grossedentata, Using Response Surface MethodologyUmair Muhammad0Hedong Lu1Juan Wang2Jinzhi Han3Xiaoyu Zhu4Zhaoxin Lu5Sultana Tayyaba6Yousef I. Hassan7College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, ChinaCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, ChinaCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, ChinaCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, ChinaCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, ChinaCollege of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, ChinaCollege of Public Administration, Nanjing Agricultural University, Nanjing 210095, ChinaGuelph Research and Development Centre, Agriculture & Agri-Food Canada, 93 Stone Road West, Guelph, ON N1G 5C9, CanadaThis work provides an optimized extraction approach intended to maximize the recovery of dihydromyricetin (DHM) from Chinese vine tea (Ampelopsis grossedentata) leaves. The presented work adopts a Box-Behnken design as a response surface methodology to understand the role and influence of specific extraction parameters including: time, temperature, and solvent composition/ethanol (%) on DHM final yields. Initially, single factor experiments were used to delineate the role of above factors (temperature, time, and solvent composition) before proceeding with three factors-three levels Box-Behnken design with 17 separate runs to assess the effect of multifactorial treatments on DHM recovery rates. The collected data shows that independent variables (solvent composition, time, and temperature) can significantly affect DHM recovery rates with maximum yields resulting from a combined 60 °C, 60% aqueous ethanol, and 180 min treatment. From the empirical point of view, the above optimized extraction protocol can substantially enhance processing and profitability margins with a minimum need of interventions or associated costs.https://www.mdpi.com/1420-3049/22/12/2250dihydromyricetinextractionfactorstemperaturesolventtime |
| spellingShingle | Umair Muhammad Hedong Lu Juan Wang Jinzhi Han Xiaoyu Zhu Zhaoxin Lu Sultana Tayyaba Yousef I. Hassan Optimizing the Maximum Recovery of Dihydromyricetin from Chinese Vine Tea, Ampelopsis grossedentata, Using Response Surface Methodology Molecules dihydromyricetin extraction factors temperature solvent time |
| title | Optimizing the Maximum Recovery of Dihydromyricetin from Chinese Vine Tea, Ampelopsis grossedentata, Using Response Surface Methodology |
| title_full | Optimizing the Maximum Recovery of Dihydromyricetin from Chinese Vine Tea, Ampelopsis grossedentata, Using Response Surface Methodology |
| title_fullStr | Optimizing the Maximum Recovery of Dihydromyricetin from Chinese Vine Tea, Ampelopsis grossedentata, Using Response Surface Methodology |
| title_full_unstemmed | Optimizing the Maximum Recovery of Dihydromyricetin from Chinese Vine Tea, Ampelopsis grossedentata, Using Response Surface Methodology |
| title_short | Optimizing the Maximum Recovery of Dihydromyricetin from Chinese Vine Tea, Ampelopsis grossedentata, Using Response Surface Methodology |
| title_sort | optimizing the maximum recovery of dihydromyricetin from chinese vine tea ampelopsis grossedentata using response surface methodology |
| topic | dihydromyricetin extraction factors temperature solvent time |
| url | https://www.mdpi.com/1420-3049/22/12/2250 |
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