Evaluation of pathogen P21 protein as a potential modulator of the protective immunity induced by Trypanosoma cruzi attenuated parasites

BACKGROUND TcP21 is a ubiquitous secreted protein of Trypanosoma cruzi and its recombinant form (rP21) promotes parasite cell invasion and acts as a phagocytosis inducer by activating actin polymerisation in the host cell. OBJECTIVE Our goal was to evaluate if the additional supplementation of rP...

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Bibliographic Details
Main Authors:	Cecilia Pérez Brandán, Andrea C Mesias, Leonardo Acuña, Thaise Lara Teixeira, Claudio Vieira da Silva
Format:	Article
Language:	English
Published:	Fundação Oswaldo Cruz (FIOCRUZ) 2019-05-01
Series:	Memorias do Instituto Oswaldo Cruz
Subjects:	Trypanosoma cruzi Chagas disease attenuated vaccine P21
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762019000100325&lng=en&tlng=en

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