GPR171 Activation Modulates Nociceptor Functions, Alleviating Pathologic Pain

GPR171 Activation Modulates Nociceptor Functions, Alleviating Pathologic Pain

Modulation of the function of somatosensory neurons is an important analgesic strategy, requiring the proposal of novel molecular targets. Many G-protein-coupled receptors (GPRs) have been deorphanized, but the receptor locations, outcomes due to their activations, and their signal transductions rem...

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Bibliographic Details
Main Authors: Pyung Sun Cho, Han Kyu Lee, Young In Choi, Seung In Choi, Ji Yeon Lim, Minseok Kim, Hyun Kim, Sung Jun Jung, Sun Wook Hwang
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Biomedicines
Subjects:
GPR171
pain
analgesia
nociceptor
TRP channel
Online Access:https://www.mdpi.com/2227-9059/9/3/256

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