Correlation analysis and gender differences of cognitive function based on mini-mental state examination (MMSE) and suicidal tendency in patients with schizophrenia
Abstract Background The aim of this study was to investigate the correlation and gender differences between cognition and suicidal tendency in patients with schizophrenia. Methods A total of 554 patients with schizophrenia were recruited. The Mini-Mental State Examination (MMSE), Positive and Negati...
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| Format: | Article |
| Language: | English |
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BMC
2024-01-01
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| Series: | BMC Psychiatry |
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| Online Access: | https://doi.org/10.1186/s12888-023-05462-9 |
| _version_ | 1797363026065620992 |
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| author | Quanfeng Zhu Xiang-Yang Zhang |
| author_facet | Quanfeng Zhu Xiang-Yang Zhang |
| author_sort | Quanfeng Zhu |
| collection | DOAJ |
| description | Abstract Background The aim of this study was to investigate the correlation and gender differences between cognition and suicidal tendency in patients with schizophrenia. Methods A total of 554 patients with schizophrenia were recruited. The Mini-Mental State Examination (MMSE), Positive and Negative Syndrome Scale (PANSS), Interpersonal Reactivity Index (IRI), Toronto Alexithymia Scale (TAS), and Insomnia Severity Index (ISI) were used to assess clinical symptoms. Results In male patients, MMSE score and the incidence of suicidal tendency were correlated (P = 0.04, OR = 1.06, 95%CI: 1.00–1.12). Among patients with cognitive dysfunction, IRI score (P = 0.01, OR = 1.04, 95%CI: 1.01–1.06), and types of antipsychotic drugs (P < 0.01, OR = 3.97, 95%CI: 1.76–8.97) in male patients were associated risk factors for suicidal ideation. Among patients without cognitive dysfunction, PANSS positive subscale score (P = 0.03, OR = 1.06, 95%CI: 1.01–1.11), and PANSS general psychopathology score (P = 0.02, OR = 1.05, 95%CI: 1.01–1.08) were associated risk factors for suicidal ideation in male patients and PANSS positive subscale score (P < 0.01, OR = 1.15, 95%CI: 1.05–1.26) were associated risk factors for suicidal ideation in female patients. Conclusions There were significant gender differences in the correlation between cognitive functioning and suicidal ideation in patients with schizophrenia. Cognitive function may play an important mediating role in other factors on suicide. |
| first_indexed | 2024-03-08T16:15:50Z |
| format | Article |
| id | doaj.art-f73d0856bfda45a6b35a27bd34cfb953 |
| institution | Directory Open Access Journal |
| issn | 1471-244X |
| language | English |
| last_indexed | 2024-03-08T16:15:50Z |
| publishDate | 2024-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Psychiatry |
| spelling | doaj.art-f73d0856bfda45a6b35a27bd34cfb9532024-01-07T12:38:30ZengBMCBMC Psychiatry1471-244X2024-01-012411810.1186/s12888-023-05462-9Correlation analysis and gender differences of cognitive function based on mini-mental state examination (MMSE) and suicidal tendency in patients with schizophreniaQuanfeng Zhu0Xiang-Yang Zhang1Affiliated Xiaoshan Hospital, Hangzhou Normal UniversityCAS Key Laboratory of Mental Health, Institute of PsychologyAbstract Background The aim of this study was to investigate the correlation and gender differences between cognition and suicidal tendency in patients with schizophrenia. Methods A total of 554 patients with schizophrenia were recruited. The Mini-Mental State Examination (MMSE), Positive and Negative Syndrome Scale (PANSS), Interpersonal Reactivity Index (IRI), Toronto Alexithymia Scale (TAS), and Insomnia Severity Index (ISI) were used to assess clinical symptoms. Results In male patients, MMSE score and the incidence of suicidal tendency were correlated (P = 0.04, OR = 1.06, 95%CI: 1.00–1.12). Among patients with cognitive dysfunction, IRI score (P = 0.01, OR = 1.04, 95%CI: 1.01–1.06), and types of antipsychotic drugs (P < 0.01, OR = 3.97, 95%CI: 1.76–8.97) in male patients were associated risk factors for suicidal ideation. Among patients without cognitive dysfunction, PANSS positive subscale score (P = 0.03, OR = 1.06, 95%CI: 1.01–1.11), and PANSS general psychopathology score (P = 0.02, OR = 1.05, 95%CI: 1.01–1.08) were associated risk factors for suicidal ideation in male patients and PANSS positive subscale score (P < 0.01, OR = 1.15, 95%CI: 1.05–1.26) were associated risk factors for suicidal ideation in female patients. Conclusions There were significant gender differences in the correlation between cognitive functioning and suicidal ideation in patients with schizophrenia. Cognitive function may play an important mediating role in other factors on suicide.https://doi.org/10.1186/s12888-023-05462-9Gender differencesSchizophreniaCognitive dysfunctionSuicidal tendencyMini-mental state examination |
| spellingShingle | Quanfeng Zhu Xiang-Yang Zhang Correlation analysis and gender differences of cognitive function based on mini-mental state examination (MMSE) and suicidal tendency in patients with schizophrenia BMC Psychiatry Gender differences Schizophrenia Cognitive dysfunction Suicidal tendency Mini-mental state examination |
| title | Correlation analysis and gender differences of cognitive function based on mini-mental state examination (MMSE) and suicidal tendency in patients with schizophrenia |
| title_full | Correlation analysis and gender differences of cognitive function based on mini-mental state examination (MMSE) and suicidal tendency in patients with schizophrenia |
| title_fullStr | Correlation analysis and gender differences of cognitive function based on mini-mental state examination (MMSE) and suicidal tendency in patients with schizophrenia |
| title_full_unstemmed | Correlation analysis and gender differences of cognitive function based on mini-mental state examination (MMSE) and suicidal tendency in patients with schizophrenia |
| title_short | Correlation analysis and gender differences of cognitive function based on mini-mental state examination (MMSE) and suicidal tendency in patients with schizophrenia |
| title_sort | correlation analysis and gender differences of cognitive function based on mini mental state examination mmse and suicidal tendency in patients with schizophrenia |
| topic | Gender differences Schizophrenia Cognitive dysfunction Suicidal tendency Mini-mental state examination |
| url | https://doi.org/10.1186/s12888-023-05462-9 |
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