An AIE-Active NIR Fluorescent Probe with Good Water Solubility for the Detection of Aβ<sub>1–42</sub> Aggregates in Alzheimer’s Disease

An AIE-Active NIR Fluorescent Probe with Good Water Solubility for the Detection of Aβ<sub>1–42</sub> Aggregates in Alzheimer’s Disease

Alzheimer’s disease (AD), an amyloid-related disease, seriously endangers the health of elderly individuals. According to current research, its main pathogenic factor is the amyloid protein, which is a kind of fibrillar aggregate formed by noncovalent self-assembly of proteins. Based on the characte...

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Bibliographic Details
Main Authors: Yan-Ming Ji, Min Hou, Wei Zhou, Zhang-Wei Ning, Yuan Zhang, Guo-Wen Xing
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Molecules
Subjects:
Alzheimer’s disease
AIE
Aβ
tetraphenylethylene
near-infrared imaging
amyloid
Online Access:https://www.mdpi.com/1420-3049/28/13/5110

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