RIP3/MLKL-mediated neuronal necroptosis induced by methamphetamine at 39°C

RIP3/MLKL-mediated neuronal necroptosis induced by methamphetamine at 39°C

Methamphetamine is one of the most prevalent drugs abused in the world. Methamphetamine abusers usually present with hyperpyrexia (39°C), hallucination and other psychiatric symptoms. However, the detailed mechanism underlying its neurotoxic action remains elusive. This study investigated the effect...

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Bibliographic Details
Main Authors: Li-Min Guo, Zhen Wang, Shi-Ping Li, Mi Wang, Wei-Tao Yan, Feng-Xia Liu, Chu-Dong Wang, Xu-Dong Zhang, Dan Chen, Jie Yan, Kun Xiong
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Neural Regeneration Research
Subjects:
gsk’872; human brain tissue; hyperpyrexia; methamphetamine; mixed lineage kinase domain-like protein; necrostatin-1; necroptosis; nerve regeneration; neural regeneration; rat cortical neurons; receptor-interacting protein-3; synergistic effect
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=5;spage=865;epage=874;aulast=Guo

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