Revisiting Viral RNA-Dependent RNA Polymerases: Insights from Recent Structural Studies

Revisiting Viral RNA-Dependent RNA Polymerases: Insights from Recent Structural Studies

RNA-dependent RNA polymerases (RdRPs) represent a distinctive yet versatile class of nucleic acid polymerases encoded by RNA viruses for the replication and transcription of their genome. The structure of the RdRP is comparable to that of a cupped right hand consisting of fingers, palm, and thumb su...

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Bibliographic Details
Main Authors: Kavitha Ramaswamy, Mariya Rashid, Selvarajan Ramasamy, Tamilselvan Jayavelu, Sangita Venkataraman
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Viruses
Subjects:
replication
polymerase
cofactors
structure
RNA viruses
inhibitors
Online Access:https://www.mdpi.com/1999-4915/14/10/2200

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