Applications of Beehive Products for Wound Repair and Skin Care

There is a long and interesting history between honeybees and humans. From the beginning, honey has been utilized not only as a sweetener, but also as an ointment and a drug to treat several diseases. Until the discovery of antibiotics, honey was a very popular product used to protect and preserve s...

Full description

Bibliographic Details
Main Authors: Simona Martinotti, Gregorio Bonsignore, Elia Ranzato
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Cosmetics
Subjects:
Online Access:https://www.mdpi.com/2079-9284/10/5/127
_version_ 1827721341517692928
author Simona Martinotti
Gregorio Bonsignore
Elia Ranzato
author_facet Simona Martinotti
Gregorio Bonsignore
Elia Ranzato
author_sort Simona Martinotti
collection DOAJ
description There is a long and interesting history between honeybees and humans. From the beginning, honey has been utilized not only as a sweetener, but also as an ointment and a drug to treat several diseases. Until the discovery of antibiotics, honey was a very popular product used to protect and preserve skin and promote wound healing, to counteract gastrointestinal pains and disorders of the oral cavity, and for other diseases. After the development of antibiotic resistance, honey again gained interest for its use in wound management. Subsequently, more recently, in vitro and in vivo studies have displayed antimicrobial, antioxidant, and other effects of honey and honeybee products, as well as protection of cardiovascular, respiratory, nervous, and gastrointestinal systems. Moreover, recent studies have demonstrated that beehive products are also able to influence the phenotype of skin cells, such as keratinocytes, fibroblasts, and endothelial cells, involved in correct wound healing. This review will characterize the great potential of honeybee products in the field of health and skin care, considering that honey is a virtually inexhaustible natural resource which people, as bees have been domesticated over the centuries, can freely access.
first_indexed 2024-03-10T21:20:12Z
format Article
id doaj.art-f740211e85f64f05927e2eeeee416c89
institution Directory Open Access Journal
issn 2079-9284
language English
last_indexed 2024-03-10T21:20:12Z
publishDate 2023-09-01
publisher MDPI AG
record_format Article
series Cosmetics
spelling doaj.art-f740211e85f64f05927e2eeeee416c892023-11-19T16:08:23ZengMDPI AGCosmetics2079-92842023-09-0110512710.3390/cosmetics10050127Applications of Beehive Products for Wound Repair and Skin CareSimona Martinotti0Gregorio Bonsignore1Elia Ranzato2Dipartimento di Scienze e Innovazione Tecnologica (DiSIT), University of Piemonte Orientale, 15121 Alessandria, ItalyDipartimento di Scienze e Innovazione Tecnologica (DiSIT), University of Piemonte Orientale, 15121 Alessandria, ItalyDipartimento di Scienze e Innovazione Tecnologica (DiSIT), University of Piemonte Orientale, 15121 Alessandria, ItalyThere is a long and interesting history between honeybees and humans. From the beginning, honey has been utilized not only as a sweetener, but also as an ointment and a drug to treat several diseases. Until the discovery of antibiotics, honey was a very popular product used to protect and preserve skin and promote wound healing, to counteract gastrointestinal pains and disorders of the oral cavity, and for other diseases. After the development of antibiotic resistance, honey again gained interest for its use in wound management. Subsequently, more recently, in vitro and in vivo studies have displayed antimicrobial, antioxidant, and other effects of honey and honeybee products, as well as protection of cardiovascular, respiratory, nervous, and gastrointestinal systems. Moreover, recent studies have demonstrated that beehive products are also able to influence the phenotype of skin cells, such as keratinocytes, fibroblasts, and endothelial cells, involved in correct wound healing. This review will characterize the great potential of honeybee products in the field of health and skin care, considering that honey is a virtually inexhaustible natural resource which people, as bees have been domesticated over the centuries, can freely access.https://www.mdpi.com/2079-9284/10/5/127aquaporin-3honeyH<sub>2</sub>O<sub>2</sub>honeydew honeypropolisroyal jelly
spellingShingle Simona Martinotti
Gregorio Bonsignore
Elia Ranzato
Applications of Beehive Products for Wound Repair and Skin Care
Cosmetics
aquaporin-3
honey
H<sub>2</sub>O<sub>2</sub>
honeydew honey
propolis
royal jelly
title Applications of Beehive Products for Wound Repair and Skin Care
title_full Applications of Beehive Products for Wound Repair and Skin Care
title_fullStr Applications of Beehive Products for Wound Repair and Skin Care
title_full_unstemmed Applications of Beehive Products for Wound Repair and Skin Care
title_short Applications of Beehive Products for Wound Repair and Skin Care
title_sort applications of beehive products for wound repair and skin care
topic aquaporin-3
honey
H<sub>2</sub>O<sub>2</sub>
honeydew honey
propolis
royal jelly
url https://www.mdpi.com/2079-9284/10/5/127
work_keys_str_mv AT simonamartinotti applicationsofbeehiveproductsforwoundrepairandskincare
AT gregoriobonsignore applicationsofbeehiveproductsforwoundrepairandskincare
AT eliaranzato applicationsofbeehiveproductsforwoundrepairandskincare